Bothmer A - Search Results

1

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.

Bunting SF, Callén E, Wong N, Chen HT, Polato F, Gunn A, Bothmer A, Feldhahn N, Fernandez-Capetillo O, Cao L, Xu X, Deng CX, Finkel T, Nussenzweig M, Stark JM, Nussenzweig A. Bunting SF, et al. Among authors: bothmer a. Cell. 2010 Apr 16;141(2):243-54. doi: 10.1016/j.cell.2010.03.012. Epub 2010 Apr 1. Cell. 2010. PMID: 20362325 Free PMC article.

2

53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination.

Bothmer A, Robbiani DF, Feldhahn N, Gazumyan A, Nussenzweig A, Nussenzweig MC. Bothmer A, et al. J Exp Med. 2010 Apr 12;207(4):855-65. doi: 10.1084/jem.20100244. Epub 2010 Apr 5. J Exp Med. 2010. PMID: 20368578 Free PMC article.

3

Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1.

Bothmer A, Robbiani DF, Di Virgilio M, Bunting SF, Klein IA, Feldhahn N, Barlow J, Chen HT, Bosque D, Callen E, Nussenzweig A, Nussenzweig MC. Bothmer A, et al. Mol Cell. 2011 May 6;42(3):319-29. doi: 10.1016/j.molcel.2011.03.019. Mol Cell. 2011. PMID: 21549309 Free PMC article.

4

RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycle.

Yamane A, Robbiani DF, Resch W, Bothmer A, Nakahashi H, Oliveira T, Rommel PC, Brown EJ, Nussenzweig A, Nussenzweig MC, Casellas R. Yamane A, et al. Among authors: bothmer a. Cell Rep. 2013 Jan 31;3(1):138-47. doi: 10.1016/j.celrep.2012.12.006. Epub 2013 Jan 3. Cell Rep. 2013. PMID: 23291097 Free PMC article.

5

AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations.

Robbiani DF, Bothmer A, Callen E, Reina-San-Martin B, Dorsett Y, Difilippantonio S, Bolland DJ, Chen HT, Corcoran AE, Nussenzweig A, Nussenzweig MC. Robbiani DF, et al. Among authors: bothmer a. Cell. 2008 Dec 12;135(6):1028-38. doi: 10.1016/j.cell.2008.09.062. Cell. 2008. PMID: 19070574 Free PMC article.

6

AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.

Robbiani DF, Bunting S, Feldhahn N, Bothmer A, Camps J, Deroubaix S, McBride KM, Klein IA, Stone G, Eisenreich TR, Ried T, Nussenzweig A, Nussenzweig MC. Robbiani DF, et al. Among authors: bothmer a. Mol Cell. 2009 Nov 25;36(4):631-41. doi: 10.1016/j.molcel.2009.11.007. Mol Cell. 2009. PMID: 19941823 Free PMC article.

7

Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.

Klein IA, Resch W, Jankovic M, Oliveira T, Yamane A, Nakahashi H, Di Virgilio M, Bothmer A, Nussenzweig A, Robbiani DF, Casellas R, Nussenzweig MC. Klein IA, et al. Among authors: bothmer a. Cell. 2011 Sep 30;147(1):95-106. doi: 10.1016/j.cell.2011.07.048. Cell. 2011. PMID: 21962510 Free PMC article.

8

Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching.

Bothmer A, Rommel PC, Gazumyan A, Polato F, Reczek CR, Muellenbeck MF, Schaetzlein S, Edelmann W, Chen PL, Brosh RM Jr, Casellas R, Ludwig T, Baer R, Nussenzweig A, Nussenzweig MC, Robbiani DF. Bothmer A, et al. J Exp Med. 2013 Jan 14;210(1):115-23. doi: 10.1084/jem.20121975. Epub 2012 Dec 17. J Exp Med. 2013. PMID: 23254285 Free PMC article.

9

Role of 53BP1 oligomerization in regulating double-strand break repair.

Lottersberger F, Bothmer A, Robbiani DF, Nussenzweig MC, de Lange T. Lottersberger F, et al. Among authors: bothmer a. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2146-51. doi: 10.1073/pnas.1222617110. Epub 2013 Jan 23. Proc Natl Acad Sci U S A. 2013. PMID: 23345425 Free PMC article.

10

DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes.

Hakim O, Resch W, Yamane A, Klein I, Kieffer-Kwon KR, Jankovic M, Oliveira T, Bothmer A, Voss TC, Ansarah-Sobrinho C, Mathe E, Liang G, Cobell J, Nakahashi H, Robbiani DF, Nussenzweig A, Hager GL, Nussenzweig MC, Casellas R. Hakim O, et al. Among authors: bothmer a. Nature. 2012 Feb 7;484(7392):69-74. doi: 10.1038/nature10909. Nature. 2012. PMID: 22314321 Free PMC article.

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