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Bis(2-hydroxybenzylidene)acetone, a potent inducer of the phase 2 response, causes apoptosis in mouse leukemia cells through a p53-independent, caspase-mediated pathway.
Cancer Lett. 2007 Jan 8;245(1-2):341-9. doi: 10.1016/j.canlet.2006.01.024. Epub 2006 Mar 6.
Cancer Lett. 2007.
PMID: 16517063
Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups.
Dinkova-Kostova AT, Massiah MA, Bozak RE, Hicks RJ, Talalay P.
Dinkova-Kostova AT, et al. Among authors: bozak re.
Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3404-9. doi: 10.1073/pnas.051632198.
Proc Natl Acad Sci U S A. 2001.
PMID: 11248091
Free PMC article.
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Phenolic Michael reaction acceptors: combined direct and indirect antioxidant defenses against electrophiles and oxidants.
Dinkova-Kostova AT, Cheah J, Samouilov A, Zweier JL, Bozak RE, Hicks RJ, Talalay P.
Dinkova-Kostova AT, et al. Among authors: bozak re.
Med Chem. 2007 May;3(3):261-8. doi: 10.2174/157340607780620680.
Med Chem. 2007.
PMID: 17504197
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Effect of the chalcone analog E,E-bis(2-hydroxybenzylidene) acetone on the 7,12-dimethylbenz[a]anthracene-induced Ha-ras gene activity in vivo.
Perjési P, Ember I, Bozak RE, Nádasi E, Rozmer Z, Varjas T, Hicks RJ.
Perjési P, et al. Among authors: bozak re.
In Vivo. 2006 Jan-Feb;20(1):141-6.
In Vivo. 2006.
PMID: 16433043
Free article.
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