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A 3D human neural cell culture system for modeling Alzheimer's disease.
Kim YH, Choi SH, D'Avanzo C, Hebisch M, Sliwinski C, Bylykbashi E, Washicosky KJ, Klee JB, Brüstle O, Tanzi RE, Kim DY. Kim YH, et al. Among authors: brustle o. Nat Protoc. 2015 Jul;10(7):985-1006. doi: 10.1038/nprot.2015.065. Epub 2015 Jun 11. Nat Protoc. 2015. PMID: 26068894 Free PMC article.
Dissecting Alzheimer's disease pathogenesis in human 2D and 3D models.
Cenini G, Hebisch M, Iefremova V, Flitsch LJ, Breitkreuz Y, Tanzi RE, Kim DY, Peitz M, Brüstle O. Cenini G, et al. Among authors: brustle o. Mol Cell Neurosci. 2021 Jan;110:103568. doi: 10.1016/j.mcn.2020.103568. Epub 2020 Oct 14. Mol Cell Neurosci. 2021. PMID: 33068718 Review.
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation.
Sheng C, Jungverdorben J, Wiethoff H, Lin Q, Flitsch LJ, Eckert D, Hebisch M, Fischer J, Kesavan J, Weykopf B, Schneider L, Holtkamp D, Beck H, Till A, Wüllner U, Ziller MJ, Wagner W, Peitz M, Brüstle O. Sheng C, et al. Among authors: brustle o. Nat Commun. 2018 Oct 2;9(1):4047. doi: 10.1038/s41467-018-06398-5. Nat Commun. 2018. PMID: 30279449 Free PMC article.
An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons.
Rhee HJ, Shaib AH, Rehbach K, Lee C, Seif P, Thomas C, Gideons E, Guenther A, Krutenko T, Hebisch M, Peitz M, Brose N, Brüstle O, Rhee JS. Rhee HJ, et al. Among authors: brustle o. Cell Rep. 2019 May 14;27(7):2212-2228.e7. doi: 10.1016/j.celrep.2019.04.059. Cell Rep. 2019. PMID: 31091457 Free article.
A Single-Cell Model for Synaptic Transmission and Plasticity in Human iPSC-Derived Neurons.
Meijer M, Rehbach K, Brunner JW, Classen JA, Lammertse HCA, van Linge LA, Schut D, Krutenko T, Hebisch M, Cornelisse LN, Sullivan PF, Peitz M, Toonen RF, Brüstle O, Verhage M. Meijer M, et al. Among authors: brustle o. Cell Rep. 2019 May 14;27(7):2199-2211.e6. doi: 10.1016/j.celrep.2019.04.058. Cell Rep. 2019. PMID: 31091456 Free article.
Embryonic stem cell-based modeling of tau pathology in human neurons.
Mertens J, Stüber K, Poppe D, Doerr J, Ladewig J, Brüstle O, Koch P. Mertens J, et al. Among authors: brustle o. Am J Pathol. 2013 May;182(5):1769-79. doi: 10.1016/j.ajpath.2013.01.043. Epub 2013 Mar 13. Am J Pathol. 2013. PMID: 23499461 Free article.
206 results