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MTN-033: a Phase 1 Study Comparing Applicator versus "as Lubricant" Delivery of Rectal Dapivirine Gel.
Ho K, Dominguez-Islas C, Szydlo D, Edick S, Macagna N, Riddler SA, Brand RM, Jacobson CE, Kramzer L, Kunjara Na Ayudhya RP, Piper J, Marzinke MA, Bauermeister J, Nuttall J, Hillier SL, Hendrix CW. Ho K, et al. Among authors: brand rm. Antimicrob Agents Chemother. 2022 Nov 15;66(11):e0081622. doi: 10.1128/aac.00816-22. Epub 2022 Oct 18. Antimicrob Agents Chemother. 2022. PMID: 36255254 Free PMC article. Clinical Trial.
Project Gel a Randomized Rectal Microbicide Safety and Acceptability Study in Young Men and Transgender Women.
McGowan I, Cranston RD, Mayer KH, Febo I, Duffill K, Siegel A, Engstrom JC, Nikiforov A, Park SY, Brand RM, Jacobson C, Giguere R, Dolezal C, Frasca T, Leu CS, Schwartz JL, Carballo-Diéguez A. McGowan I, et al. Among authors: brand rm. PLoS One. 2016 Jun 30;11(6):e0158310. doi: 10.1371/journal.pone.0158310. eCollection 2016. PLoS One. 2016. PMID: 27362788 Free PMC article. Clinical Trial.
The pharmacokinetics, pharmacodynamics, and mucosal responses to maraviroc-containing pre-exposure prophylaxis regimens in MSM.
McGowan I, Wilkin T, Landovitz RJ, Wu C, Chen Y, Marzinke MA, Hendrix CW, Richardson P, Eshleman SH, Andrade A, Chege W, Anderson PL, McCauley M, Farley J, Mayer KH, Anton P, Brand RM, Cranston RD, Gulick R. McGowan I, et al. Among authors: brand rm. AIDS. 2019 Feb 1;33(2):237-246. doi: 10.1097/QAD.0000000000002038. AIDS. 2019. PMID: 30557160 Free PMC article. Clinical Trial.
Brief Report: Dipyridamole Decreases Gut Mucosal Regulatory T-Cell Frequencies Among People With HIV on Antiretroviral Therapy.
Mallarino-Haeger C, Abebe KZ, Jackson EK, Zyhowski A, Klamar-Blain C, Cyktor JC, Comer D, Brand RM, Gillespie DG, Holleran K, Mellors JW, McGowan I, Riddler SA, Macatangay BJC. Mallarino-Haeger C, et al. Among authors: brand rm. J Acquir Immune Defic Syndr. 2020 Dec 15;85(5):665-669. doi: 10.1097/QAI.0000000000002488. J Acquir Immune Defic Syndr. 2020. PMID: 33177477 Free PMC article. Clinical Trial.
Higher colorectal tissue HIV infectivity in cisgender women compared with MSM before and during oral preexposure prophylaxis.
Sekabira R, McGowan I, Yuhas K, Brand RM, Marzinke MA, Manabe YC, Frank I, Eron J, Landovitz RJ, Anton P, Cranston RD, Anderson P, Mayer KH, Amico KR, Wilkin TJ, Chege W, Kekitiinwa AR, McCauley M, Gulick RM, Hendrix CW. Sekabira R, et al. Among authors: brand rm. AIDS. 2021 Aug 1;35(10):1585-1595. doi: 10.1097/QAD.0000000000002907. AIDS. 2021. PMID: 33831911 Free PMC article.
A Randomized, Open-Label, Crossover Phase 1 Safety and Pharmacokinetic Study of Oral Maraviroc and Maraviroc 1% Gel (the CHARM-03 Study).
McGowan IM, Chawki S, Hendrix CW, Anton PA, Marzinke MA, Brand RM, Engstrom JC, Rohan LC, Abebe KZ, Richardson-Harman N, Siegel A, Reinhart A, Steytler J, Stall R, Spiegel H, Chen B, Achilles SL, Jacobson CE, Khanukova E, Cranston RD. McGowan IM, et al. Among authors: brand rm. AIDS Res Hum Retroviruses. 2022 Apr;38(4):269-278. doi: 10.1089/AID.2021.0096. Epub 2021 Sep 14. AIDS Res Hum Retroviruses. 2022. PMID: 34384282 Free PMC article. Clinical Trial.
A Randomized, Double Blind, Placebo-Controlled, Phase 1 Safety, and Pharmacokinetic Study of Dapivirine Gel (0.05%) Administered Rectally to HIV-1 Seronegative Adults (MTN-026).
Cranston RD, Brown E, Bauermeister J, Dunne EF, Hoesley C, Ho K, Johnson S, Lucas J, Dominguez-Islas C, Gundacker H, Peda M, Jacobson CE, Kramzer L, Singh D, Dezzutti CS, Kunjara Na Ayudhya RP, Brand RM, Wang L, Marzinke MA, Piper J, Devlin B, Nuttall J, McGowan I, Hendrix CW. Cranston RD, et al. Among authors: brand rm. AIDS Res Hum Retroviruses. 2022 Apr;38(4):257-268. doi: 10.1089/AID.2021.0071. Epub 2021 Dec 6. AIDS Res Hum Retroviruses. 2022. PMID: 34498980 Free PMC article. Clinical Trial.
An Open-Label Pharmacokinetic and Pharmacodynamic Assessment of Tenofovir Gel and Oral Emtricitabine/Tenofovir Disoproxil Fumarate.
McGowan IM, Kunjara Na Ayudhya RP, Brand RM, Marzinke MA, Hendrix CW, Johnson S, Piper J, Holtz TH, Curlin ME, Chitwarakorn A, Raengsakulrach B, Doncel G, Schwartz JL, Rooney JF, Cranston RD. McGowan IM, et al. Among authors: brand rm. AIDS Res Hum Retroviruses. 2022 Apr;38(4):279-287. doi: 10.1089/AID.2021.0115. Epub 2021 Oct 29. AIDS Res Hum Retroviruses. 2022. PMID: 34541872 Free PMC article. Clinical Trial.
Comparative Pharmacokinetics and Local Tolerance of Tenofovir Alafenamide (TAF) From Subcutaneous Implant in Rabbits, Dogs, and Macaques.
Gatto GJ, Krovi A, Li L, Massud I, Holder A, Gary J, Mills P, Mitchell J, Luecke E, Demkovich ZR, Heneine W, García-Lerma JG, Marzinke MA, Brand RM, Dobard CW, Johnson LM, Van Der Straten A. Gatto GJ, et al. Among authors: brand rm. Front Pharmacol. 2022 Jul 19;13:923954. doi: 10.3389/fphar.2022.923954. eCollection 2022. Front Pharmacol. 2022. PMID: 35928266 Free PMC article.
90 results