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A mitochondrial long-chain fatty acid oxidation defect leads to transfer RNA uncharging and activation of the integrated stress response in the mouse heart.
Ranea-Robles P, Pavlova NN, Bender A, Pereyra AS, Ellis JM, Stauffer B, Yu C, Thompson CB, Argmann C, Puchowicz M, Houten SM. Ranea-Robles P, et al. Among authors: stauffer b. Cardiovasc Res. 2022 Dec 29;118(16):3198-3210. doi: 10.1093/cvr/cvac050. Cardiovasc Res. 2022. PMID: 35388887 Free PMC article.
Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex.
Leandro J, Khamrui S, Wang H, Suebsuwong C, Nemeria NS, Huynh K, Moustakim M, Secor C, Wang M, Dodatko T, Stauffer B, Wilson CG, Yu C, Arkin MR, Jordan F, Sanchez R, DeVita RJ, Lazarus MB, Houten SM. Leandro J, et al. Among authors: stauffer b. ACS Chem Biol. 2020 Aug 21;15(8):2041-2047. doi: 10.1021/acschembio.0c00114. Epub 2020 Jul 9. ACS Chem Biol. 2020. PMID: 32633484 Free PMC article.
An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters.
Cui G, Hong J, Chung-Davidson YW, Infield D, Xu X, Li J, Simhaev L, Khazanov N, Stauffer B, Imhoff B, Cottrill K, Blalock JE, Li W, Senderowitz H, Sorscher E, McCarty NA, Gaggar A. Cui G, et al. Among authors: stauffer b. Dev Cell. 2019 Nov 18;51(4):421-430.e3. doi: 10.1016/j.devcel.2019.09.017. Epub 2019 Oct 31. Dev Cell. 2019. PMID: 31679858 Free PMC article.
Potentiators exert distinct effects on human, murine, and Xenopus CFTR.
Cui G, Khazanov N, Stauffer BB, Infield DT, Imhoff BR, Senderowitz H, McCarty NA. Cui G, et al. Among authors: stauffer bb. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L192-207. doi: 10.1152/ajplung.00056.2016. Epub 2016 Jun 10. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27288484 Free PMC article.
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