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Early postnatal GABAA receptor modulation reverses deficits in neuronal maturation in a conditional neurodevelopmental mouse model of DISC1.
Saito A, Taniguchi Y, Rannals MD, Merfeld EB, Ballinger MD, Koga M, Ohtani Y, Gurley DA, Sedlak TW, Cross A, Moss SJ, Brandon NJ, Maher BJ, Kamiya A. Saito A, et al. Among authors: brandon nj. Mol Psychiatry. 2016 Oct;21(10):1449-59. doi: 10.1038/mp.2015.203. Epub 2016 Jan 5. Mol Psychiatry. 2016. PMID: 26728564 Free PMC article.
DISC1 regulates trafficking and processing of APP and Aβ generation.
Shahani N, Seshadri S, Jaaro-Peled H, Ishizuka K, Hirota-Tsuyada Y, Wang Q, Koga M, Sedlak TW, Korth C, Brandon NJ, Kamiya A, Subramaniam S, Tomoda T, Sawa A. Shahani N, et al. Among authors: brandon nj. Mol Psychiatry. 2015 Jul;20(7):874-9. doi: 10.1038/mp.2014.100. Epub 2014 Sep 16. Mol Psychiatry. 2015. PMID: 25224257 Free PMC article.
The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function.
Wang Q, Charych EI, Pulito VL, Lee JB, Graziane NM, Crozier RA, Revilla-Sanchez R, Kelly MP, Dunlop AJ, Murdoch H, Taylor N, Xie Y, Pausch M, Hayashi-Takagi A, Ishizuka K, Seshadri S, Bates B, Kariya K, Sawa A, Weinberg RJ, Moss SJ, Houslay MD, Yan Z, Brandon NJ. Wang Q, et al. Among authors: brandon nj. Mol Psychiatry. 2011 Oct;16(10):1006-23. doi: 10.1038/mp.2010.87. Epub 2010 Sep 14. Mol Psychiatry. 2011. PMID: 20838393 Free PMC article.
DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan.
Porteous DJ, Thomson PA, Millar JK, Evans KL, Hennah W, Soares DC, McCarthy S, McCombie WR, Clapcote SJ, Korth C, Brandon NJ, Sawa A, Kamiya A, Roder JC, Lawrie SM, McIntosh AM, St Clair D, Blackwood DH. Porteous DJ, et al. Among authors: brandon nj. Mol Psychiatry. 2014 Feb;19(2):141-3. doi: 10.1038/mp.2013.160. Mol Psychiatry. 2014. PMID: 24457522 Free PMC article. No abstract available.
152 results