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Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours.
Brenner E, Schörg BF, Ahmetlić F, Wieder T, Hilke FJ, Simon N, Schroeder C, Demidov G, Riedel T, Fehrenbacher B, Schaller M, Forschner A, Eigentler T, Niessner H, Sinnberg T, Böhm KS, Hömberg N, Braumüller H, Dauch D, Zwirner S, Zender L, Sonanini D, Geishauser A, Bauer J, Eichner M, Jarick KJ, Beilhack A, Biskup S, Döcker D, Schadendorf D, Quintanilla-Martinez L, Pichler BJ, Kneilling M, Mocikat R, Röcken M. Brenner E, et al. Among authors: braumuller h. Nat Commun. 2020 Mar 12;11(1):1335. doi: 10.1038/s41467-020-14987-6. Nat Commun. 2020. PMID: 32165639 Free PMC article.
TNFR1 signaling and IFN-gamma signaling determine whether T cells induce tumor dormancy or promote multistage carcinogenesis.
Müller-Hermelink N, Braumüller H, Pichler B, Wieder T, Mailhammer R, Schaak K, Ghoreschi K, Yazdi A, Haubner R, Sander CA, Mocikat R, Schwaiger M, Förster I, Huss R, Weber WA, Kneilling M, Röcken M. Müller-Hermelink N, et al. Among authors: braumuller h. Cancer Cell. 2008 Jun;13(6):507-18. doi: 10.1016/j.ccr.2008.04.001. Cancer Cell. 2008. PMID: 18538734 Free article.
T cell-mediated help against tumors.
Wieder T, Braumüller H, Kneilling M, Pichler B, Röcken M. Wieder T, et al. Among authors: braumuller h. Cell Cycle. 2008 Oct;7(19):2974-7. doi: 10.4161/cc.7.19.6798. Epub 2008 Oct 15. Cell Cycle. 2008. PMID: 18838866 Review.
T-helper-1-cell cytokines drive cancer into senescence.
Braumüller H, Wieder T, Brenner E, Aßmann S, Hahn M, Alkhaled M, Schilbach K, Essmann F, Kneilling M, Griessinger C, Ranta F, Ullrich S, Mocikat R, Braungart K, Mehra T, Fehrenbacher B, Berdel J, Niessner H, Meier F, van den Broek M, Häring HU, Handgretinger R, Quintanilla-Martinez L, Fend F, Pesic M, Bauer J, Zender L, Schaller M, Schulze-Osthoff K, Röcken M. Braumüller H, et al. Nature. 2013 Feb 21;494(7437):361-5. doi: 10.1038/nature11824. Epub 2013 Feb 3. Nature. 2013. PMID: 23376950 Free article.
Changing T-cell enigma: cancer killing or cancer control?
Wieder T, Braumüller H, Brenner E, Zender L, Röcken M. Wieder T, et al. Among authors: braumuller h. Cell Cycle. 2013 Oct 1;12(19):3146-53. doi: 10.4161/cc.26060. Epub 2013 Aug 26. Cell Cycle. 2013. PMID: 24013429 Free PMC article.
Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation.
Schilbach K, Alkhaled M, Welker C, Eckert F, Blank G, Ziegler H, Sterk M, Müller F, Sonntag K, Wieder T, Braumüller H, Schmitt J, Eyrich M, Schleicher S, Seitz C, Erbacher A, Pichler BJ, Müller H, Tighe R, Lim A, Gillies SD, Strittmatter W, Röcken M, Handgretinger R. Schilbach K, et al. Among authors: braumuller h. Oncoimmunology. 2015 Mar 19;4(7):e1014760. doi: 10.1080/2162402X.2015.1014760. eCollection 2015 Jul. Oncoimmunology. 2015. PMID: 26140238 Free PMC article.
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