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Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain.
van der Vos KE, Abels ER, Zhang X, Lai C, Carrizosa E, Oakley D, Prabhakar S, Mardini O, Crommentuijn MH, Skog J, Krichevsky AM, Stemmer-Rachamimov A, Mempel TR, El Khoury J, Hickman SE, Breakefield XO. van der Vos KE, et al. Among authors: breakefield xo. Neuro Oncol. 2016 Jan;18(1):58-69. doi: 10.1093/neuonc/nov244. Epub 2015 Oct 3. Neuro Oncol. 2016. PMID: 26433199 Free PMC article.
Multidimensional communication in the microenvirons of glioblastoma.
Broekman ML, Maas SLN, Abels ER, Mempel TR, Krichevsky AM, Breakefield XO. Broekman ML, et al. Among authors: breakefield xo. Nat Rev Neurol. 2018 Aug;14(8):482-495. doi: 10.1038/s41582-018-0025-8. Nat Rev Neurol. 2018. PMID: 29985475 Free PMC article. Review.
Glioma EVs Contribute to Immune Privilege in the Brain.
Abels ER, Broekman MLD, Breakefield XO, Maas SLN. Abels ER, et al. Among authors: breakefield xo. Trends Cancer. 2019 Jul;5(7):393-396. doi: 10.1016/j.trecan.2019.05.006. Epub 2019 Jun 4. Trends Cancer. 2019. PMID: 31311653 Free PMC article. Review.
Glioblastoma hijacks microglial gene expression to support tumor growth.
Maas SLN, Abels ER, Van De Haar LL, Zhang X, Morsett L, Sil S, Guedes J, Sen P, Prabhakar S, Hickman SE, Lai CP, Ting DT, Breakefield XO, Broekman MLD, El Khoury J. Maas SLN, et al. Among authors: breakefield xo. J Neuroinflammation. 2020 Apr 16;17(1):120. doi: 10.1186/s12974-020-01797-2. J Neuroinflammation. 2020. PMID: 32299465 Free PMC article.
Preventing growth of brain tumors by creating a zone of resistance.
Maguire CA, Meijer DH, LeRoy SG, Tierney LA, Broekman ML, Costa FF, Breakefield XO, Stemmer-Rachamimov A, Sena-Esteves M. Maguire CA, et al. Among authors: breakefield xo. Mol Ther. 2008 Oct;16(10):1695-702. doi: 10.1038/mt.2008.168. Epub 2008 Aug 19. Mol Ther. 2008. PMID: 18714312 Free PMC article.
Glioblastomas exploit truncated O-linked glycans for local and distant immune modulation via the macrophage galactose-type lectin.
Dusoswa SA, Verhoeff J, Abels E, Méndez-Huergo SP, Croci DO, Kuijper LH, de Miguel E, Wouters VMCJ, Best MG, Rodriguez E, Cornelissen LAM, van Vliet SJ, Wesseling P, Breakefield XO, Noske DP, Würdinger T, Broekman MLD, Rabinovich GA, van Kooyk Y, Garcia-Vallejo JJ. Dusoswa SA, et al. Among authors: breakefield xo. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3693-3703. doi: 10.1073/pnas.1907921117. Epub 2020 Feb 4. Proc Natl Acad Sci U S A. 2020. PMID: 32019882 Free PMC article.
469 results