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Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank.
Coleman JRI, Peyrot WJ, Purves KL, Davis KAS, Rayner C, Choi SW, Hübel C, Gaspar HA, Kan C, Van der Auwera S, Adams MJ, Lyall DM, Choi KW; on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Dunn EC, Vassos E, Danese A, Maughan B, Grabe HJ, Lewis CM, O'Reilly PF, McIntosh AM, Smith DJ, Wray NR, Hotopf M, Eley TC, Breen G. Coleman JRI, et al. Among authors: breen g. Mol Psychiatry. 2020 Jul;25(7):1430-1446. doi: 10.1038/s41380-019-0546-6. Epub 2020 Jan 23. Mol Psychiatry. 2020. PMID: 31969693 Free PMC article.
The Depression Network (DeNT) Study: methodology and sociodemographic characteristics of the first 470 affected sibling pairs from a large multi-site linkage genetic study.
Farmer A, Breen G, Brewster S, Craddock N, Gill M, Korszun A, Maier W, Middleton L, Mors O, Owen M, Perry J, Preisig M, Rietschel M, Reich T, Jones L, Jones I, McGuffin P. Farmer A, et al. Among authors: breen g. BMC Psychiatry. 2004 Dec 9;4:42. doi: 10.1186/1471-244X-4-42. BMC Psychiatry. 2004. PMID: 15588307 Free PMC article.
Whole genome linkage scan of recurrent depressive disorder from the depression network study.
McGuffin P, Knight J, Breen G, Brewster S, Boyd PR, Craddock N, Gill M, Korszun A, Maier W, Middleton L, Mors O, Owen MJ, Perry J, Preisig M, Reich T, Rice J, Rietschel M, Jones L, Sham P, Farmer AE. McGuffin P, et al. Among authors: breen g. Hum Mol Genet. 2005 Nov 15;14(22):3337-45. doi: 10.1093/hmg/ddi363. Epub 2005 Oct 3. Hum Mol Genet. 2005. PMID: 16203746
A common haplotype of the dopamine transporter gene associated with attention-deficit/hyperactivity disorder and interacting with maternal use of alcohol during pregnancy.
Brookes KJ, Mill J, Guindalini C, Curran S, Xu X, Knight J, Chen CK, Huang YS, Sethna V, Taylor E, Chen W, Breen G, Asherson P. Brookes KJ, et al. Among authors: breen g. Arch Gen Psychiatry. 2006 Jan;63(1):74-81. doi: 10.1001/archpsyc.63.1.74. Arch Gen Psychiatry. 2006. PMID: 16389200
No association between a common haplotype of the 6 and 10-repeat alleles in intron 8 and the 3'UTR of the DAT1 gene and adult attention deficit hyperactivity disorder.
Brüggemann D, Sobanski E, Alm B, Schubert T, Schmalzried H, Philipsen A, Breen G, Becker T, Georgi A, Skowronek MH, Schulze TG, Treutlein J, Rietschel M. Brüggemann D, et al. Among authors: breen g. Psychiatr Genet. 2007 Apr;17(2):121. doi: 10.1097/YPG.0b013e32801231d4. Psychiatr Genet. 2007. PMID: 17413453 No abstract available.
Towards "systems psychiatry".
Breen G, McGuffin P, Simmons A. Breen G, et al. Braz J Psychiatry. 2008 Jun;30(2):97-8. doi: 10.1590/s1516-44462008000200002. Braz J Psychiatry. 2008. PMID: 18592104 Free article. No abstract available.
Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder.
Byrne EM; Psychiatric Genetics Consortium Major Depressive Disorder Working Group; Raheja UK, Stephens SH, Heath AC, Madden PA, Vaswani D, Nijjar GV, Ryan KA, Youssufi H, Gehrman PR, Shuldiner AR, Martin NG, Montgomery GW, Wray NR, Nelson EC, Mitchell BD, Postolache TT. Byrne EM, et al. J Clin Psychiatry. 2015 Feb;76(2):128-34. doi: 10.4088/JCP.14m08981. J Clin Psychiatry. 2015. PMID: 25562672 Free PMC article.
Clinical characteristics of patients assessed within an Improving Access to Psychological Therapies (IAPT) service: results from a naturalistic cohort study (Predicting Outcome Following Psychological Therapy; PROMPT).
Hepgul N, King S, Amarasinghe M, Breen G, Grant N, Grey N, Hotopf M, Moran P, Pariante CM, Tylee A, Wingrove J, Young AH, Cleare AJ. Hepgul N, et al. Among authors: breen g. BMC Psychiatry. 2016 Feb 27;16:52. doi: 10.1186/s12888-016-0736-6. BMC Psychiatry. 2016. PMID: 26920578 Free PMC article.
Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations.
Milaneschi Y, Lamers F, Peyrot WJ, Baune BT, Breen G, Dehghan A, Forstner AJ, Grabe HJ, Homuth G, Kan C, Lewis C, Mullins N, Nauck M, Pistis G, Preisig M, Rivera M, Rietschel M, Streit F, Strohmaier J, Teumer A, Van der Auwera S, Wray NR, Boomsma DI, Penninx BWJH; CHARGE Inflammation Working Group and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Milaneschi Y, et al. Among authors: breen g. JAMA Psychiatry. 2017 Dec 1;74(12):1214-1225. doi: 10.1001/jamapsychiatry.2017.3016. JAMA Psychiatry. 2017. PMID: 29049554 Free PMC article.
573 results