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Targeting the Ubiquitin-Proteasome System Using the UBA1 Inhibitor TAK-243 is a Potential Therapeutic Strategy for Small-Cell Lung Cancer.
Majeed S, Aparnathi MK, Nixon KCJ, Venkatasubramanian V, Rahman F, Song L, Weiss J, Barayan R, Sugumar V, Barghout SH, Pearson JD, Bremner R, Schimmer AD, Tsao MS, Liu G, Lok BH. Majeed S, et al. Among authors: bremner r. Clin Cancer Res. 2022 May 2;28(9):1966-1978. doi: 10.1158/1078-0432.CCR-21-0344. Clin Cancer Res. 2022. PMID: 35165102 Free PMC article.
Functional genomics identifies new synergistic therapies for retinoblastoma.
Aubry A, Pearson JD, Huang K, Livne-Bar I, Ahmad M, Jagadeesan M, Khetan V, Ketela T, Brown KR, Yu T, Lu S, Wrana JL, Moffat J, Bremner R. Aubry A, et al. Among authors: bremner r. Oncogene. 2020 Jul;39(31):5338-5357. doi: 10.1038/s41388-020-1372-7. Epub 2020 Jun 22. Oncogene. 2020. PMID: 32572160 Free PMC article.
A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2.
Aynaud MM, Hernandez JJ, Barutcu S, Braunschweig U, Chan K, Pearson JD, Trcka D, Prosser SL, Kim J, Barrios-Rodiles M, Jen M, Song S, Shen J, Bruce C, Hazlett B, Poutanen S, Attisano L, Bremner R, Blencowe BJ, Mazzulli T, Han H, Pelletier L, Wrana JL. Aynaud MM, et al. Among authors: bremner r. Nat Commun. 2021 Mar 3;12(1):1405. doi: 10.1038/s41467-021-21653-y. Nat Commun. 2021. PMID: 33658502 Free PMC article.
Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methods.
Pearson JD, Trcka D, Lu S, Hyduk SJ, Jen M, Aynaud MM, Hernández JJ, Peidis P, Barrios-Rodiles M, Chan K, Woodgett J, Mazzulli T, Attisano L, Pelletier L, Cybulsky MI, Wrana JL, Bremner R. Pearson JD, et al. Among authors: bremner r. Virol J. 2021 May 17;18(1):99. doi: 10.1186/s12985-021-01574-4. Virol J. 2021. PMID: 34001180 Free PMC article.
Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity.
Pearson JD, Huang K, Pacal M, McCurdy SR, Lu S, Aubry A, Yu T, Wadosky KM, Zhang L, Wang T, Gregorieff A, Ahmad M, Dimaras H, Langille E, Cole SPC, Monnier PP, Lok BH, Tsao MS, Akeno N, Schramek D, Wikenheiser-Brokamp KA, Knudsen ES, Witkiewicz AK, Wrana JL, Goodrich DW, Bremner R. Pearson JD, et al. Among authors: bremner r. Cancer Cell. 2021 Aug 9;39(8):1115-1134.e12. doi: 10.1016/j.ccell.2021.06.016. Epub 2021 Jul 21. Cancer Cell. 2021. PMID: 34270926 Free PMC article.
InVision: An optimized tissue clearing approach for three-dimensional imaging and analysis of intact rodent eyes.
Gurdita A, Nickerson PEB, Pokrajac NT, Ortín-Martínez A, Samuel Tsai EL, Comanita L, Yan NE, Dolati P, Tachibana N, Liu ZC, Pearson JD, Chen D, Bremner R, Wallace VA. Gurdita A, et al. Among authors: bremner r. iScience. 2021 Jul 26;24(8):102905. doi: 10.1016/j.isci.2021.102905. eCollection 2021 Aug 20. iScience. 2021. PMID: 34430805 Free PMC article.
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[No authors listed] [No authors listed] PMID: 34701522
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[No authors listed] [No authors listed] PMID: 35190820
302 results