Brendan Frett[Author] - Search Results

Year	Number of Results
2012	1
2013	3
2014	5
2015	3
2016	1
2017	3
2018	6
2019	3
2020	10
2021	7
2022	5
2023	1
2024	3

1

Targeting TGF-β: triumphs and challenges.

Acharya B, Miah S, Frett B. Acharya B, et al. Among authors: frett b. Future Med Chem. 2022 Apr;14(7):455-458. doi: 10.4155/fmc-2021-0344. Epub 2022 Feb 13. Future Med Chem. 2022. PMID: 35152715 No abstract available.

2

The Exploration of Chirality for Improved Druggability within the Human Kinome.

Saha D, Kharbanda A, Yan W, Lakkaniga NR, Frett B, Li HY. Saha D, et al. Among authors: frett b. J Med Chem. 2020 Jan 23;63(2):441-469. doi: 10.1021/acs.jmedchem.9b00640. Epub 2019 Oct 9. J Med Chem. 2020. PMID: 31550151 Free PMC article. Review.

3

FLT3 inhibitors for acute myeloid leukemia: successes, defeats, and emerging paradigms.

Acharya B, Saha D, Armstrong D, Lakkaniga NR, Frett B. Acharya B, et al. Among authors: frett b. RSC Med Chem. 2022 May 23;13(7):798-816. doi: 10.1039/d2md00067a. eCollection 2022 Jul 20. RSC Med Chem. 2022. PMID: 35923716 Free PMC article. Review.

4

An updated patent review of rearranged during transfection (RET) kinase inhibitors (2016-present).

Acharya B, Frett B. Acharya B, et al. Among authors: frett b. Expert Opin Ther Pat. 2022 Oct;32(10):1067-1077. doi: 10.1080/13543776.2022.2132851. Epub 2022 Oct 18. Expert Opin Ther Pat. 2022. PMID: 36198171 Review.

5

Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.

Saha D, Ryan KR, Lakkaniga NR, Acharya B, Garcia NG, Smith EL, Frett B. Saha D, et al. Among authors: frett b. J Med Chem. 2021 Aug 26;64(16):11747-11773. doi: 10.1021/acs.jmedchem.0c02167. Epub 2021 Aug 17. J Med Chem. 2021. PMID: 34402300 Free PMC article. Review.

6

Recent advances in the development of polycyclic skeletons via Ugi reaction cascades.

Lei J, Meng JP, Tang DY, Frett B, Chen ZZ, Xu ZG. Lei J, et al. Among authors: frett b. Mol Divers. 2018 May;22(2):503-516. doi: 10.1007/s11030-017-9811-2. Epub 2018 Jan 16. Mol Divers. 2018. PMID: 29340996 Review.

7

(Z)-N-tert-Butyl-2-(4-meth-oxy-anilino)-N'-(4-meth-oxy-phen-yl)-2-phenyl-acetimidamide.

Roberts SA, Saha B, Frett B, Li HY. Roberts SA, et al. Among authors: frett b. Acta Crystallogr Sect E Struct Rep Online. 2013 May 18;69(Pt 6):o902. doi: 10.1107/S1600536813012877. Print 2013 Jun 1. Acta Crystallogr Sect E Struct Rep Online. 2013. PMID: 23795077 Free PMC article.

8

Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma.

McCrury M, Swafford K, Shuttleworth SL, Mehdi SH, Acharya B, Saha D, Naceanceno K, Byrum SD, Storey AJ, Xu YZ, Doshier C, Patel V, Post GR, De Loose A, Rodriguez A, Shultz LD, Zhan F, Yoon D, Frett B, Kendrick S. McCrury M, et al. Among authors: frett b. Mol Cancer Ther. 2024 Mar 4;23(3):316-329. doi: 10.1158/1535-7163.MCT-23-0299. Mol Cancer Ther. 2024. PMID: 37816504

9

Targeting mutant KRAS for anticancer therapeutics: a review of novel small molecule modulators.

Wang Y, Kaiser CE, Frett B, Li HY. Wang Y, et al. Among authors: frett b. J Med Chem. 2013 Jul 11;56(13):5219-30. doi: 10.1021/jm3017706. Epub 2013 Apr 23. J Med Chem. 2013. PMID: 23566315 Free PMC article. Review.

10

Kinase inhibitor macrocycles: a perspective on limiting conformational flexibility when targeting the kinome with small molecules.

Acharya B, Saha D, Armstrong D, Jabali B, Hanafi M, Herrera-Rueda A, Lakkaniga NR, Frett B. Acharya B, et al. Among authors: frett b. RSC Med Chem. 2023 Dec 12;15(2):399-415. doi: 10.1039/d3md00457k. eCollection 2024 Feb 21. RSC Med Chem. 2023. PMID: 38389874 Review.

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