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Identification and Optimization of RNA-Splicing Modulators as Huntingtin Protein-Lowering Agents for the Treatment of Huntington's Disease.
Liu L, Malagu K, Haughan AF, Khetarpal V, Stott AJ, Esmieu W, Vater HD, Webster SJ, Van de Poël AJ, Clissold C, Cosgrove B, Sutton B, Spencer JA, Breccia P, Gancia E, Bonomo S, Ladduwahetty T, Lazari O, Patel H, Atton HC, Clifton S, Mota DM, Magnani D, O'Neill A, Stebbeds M, Macabuag N, Todd D, Herva ME, Mitchell P, Visser M, Compte Sancerni S, Grand Moursel L, da Silva M, Kritikou E, Heikkinen TT, Bolkvadze T, Fodale V, Spadafora D, Daldin M, Bresciani A, Mangette JE, Doherty EM, Lee MR, Herbst T, Monteagudo E, Macdonald D, Plotnikov NV, Chambers M, McAllister G, Muňoz-Sanjuan I, Dominguez C. Liu L, et al. Among authors: bresciani a. J Med Chem. 2023 Sep 28;66(18):13205-13246. doi: 10.1021/acs.jmedchem.3c01173. Epub 2023 Sep 15. J Med Chem. 2023. PMID: 37712656
A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation.
Acchioni C, Acchioni M, Mancini F, Amendola A, Marsili G, Tirelli V, Gwee CP, Chan KW, Sandini S, Bisbocci M, Mysara M, ElHefnawi M, Sanchez M, Venturi G, Barreca ML, Manfroni G, Bresciani A, Vasudevan SG, Sgarbanti M. Acchioni C, et al. Among authors: bresciani a. Virology. 2023 Jun;583:1-13. doi: 10.1016/j.virol.2023.03.016. Epub 2023 Apr 5. Virology. 2023. PMID: 37060797 Free article.
Efficacy of recanalization therapy for ischemic stroke: multicenter hospital network experience.
Briganti F, Tortora M, Tortora F, Elefante A, Loiudice G, Marseglia M, Buono G, Rizzuti M, Iodice R, Manganelli F, Diurno F, Numis FG, Ferrara L, Bruno C, Bresciani A, Caranci F, Franco D, Vaiano C, D'Onofrio G, Scala P, Raucci R, Silvestro E. Briganti F, et al. Among authors: bresciani a. Radiol Med. 2023 Mar;128(3):357-361. doi: 10.1007/s11547-023-01599-5. Epub 2023 Feb 8. Radiol Med. 2023. PMID: 36752988 Free PMC article.
Identification of HSPB8 modulators counteracting misfolded protein accumulation in neurodegenerative diseases.
Chierichetti M, Cerretani M, Ciammaichella A, Crippa V, Rusmini P, Ferrari V, Tedesco B, Casarotto E, Cozzi M, Mina F, Pramaggiore P, Galbiati M, Piccolella M, Bresciani A, Cristofani R, Poletti A. Chierichetti M, et al. Among authors: bresciani a. Life Sci. 2023 Jun 1;322:121323. doi: 10.1016/j.lfs.2022.121323. Epub 2022 Dec 24. Life Sci. 2023. PMID: 36574942 Free article.
105 results