Brink A - Search Results

1

Tests for genotoxicity and mutagenicity of furan and its metabolite cis-2-butene-1,4-dial in L5178Y tk+/- mouse lymphoma cells.

Kellert M, Brink A, Richter I, Schlatter J, Lutz WK. Kellert M, et al. Among authors: brink a. Mutat Res. 2008 Dec 8;657(2):127-32. doi: 10.1016/j.mrgentox.2008.08.014. Epub 2008 Aug 28. Mutat Res. 2008. PMID: 18804178

2

Time-dependent effects of sodium arsenite on DNA breakage and apoptosis observed in the comet assay.

Brink A, Schulz B, Kobras K, Lutz WK, Stopper H. Brink A, et al. Mutat Res. 2006 Feb 28;603(2):121-8. doi: 10.1016/j.mrgentox.2005.10.015. Epub 2005 Dec 27. Mutat Res. 2006. PMID: 16384727

3

Biological significance of DNA adducts investigated by simultaneous analysis of different endpoints of genotoxicity in L5178Y mouse lymphoma cells treated with methyl methanesulfonate.

Brink A, Schulz B, Stopper H, Lutz WK. Brink A, et al. Mutat Res. 2007 Dec 1;625(1-2):94-101. doi: 10.1016/j.mrfmmm.2007.05.007. Epub 2007 May 21. Mutat Res. 2007. PMID: 17586535

4

Biological significance of DNA adducts: comparison of increments over background for various biomarkers of genotoxicity in L5178Y tk(+/-) mouse lymphoma cells treated with hydrogen peroxide and cumene hydroperoxide.

Brink A, Richter I, Lutz U, Wanek P, Stopper H, Lutz WK. Brink A, et al. Mutat Res. 2009 Aug;678(2):123-8. doi: 10.1016/j.mrgentox.2009.06.001. Epub 2009 Jun 16. Mutat Res. 2009. PMID: 19539047

5

Simultaneous determination of O6-methyl-2'-deoxyguanosine, 8-oxo-7,8-dihydro-2'-deoxyguanosine, and 1,N6-etheno-2'-deoxyadenosine in DNA using on-line sample preparation by HPLC column switching coupled to ESI-MS/MS.

Brink A, Lutz U, Völkel W, Lutz WK. Brink A, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Jan 18;830(2):255-61. doi: 10.1016/j.jchromb.2005.10.046. Epub 2005 Nov 17. J Chromatogr B Analyt Technol Biomed Life Sci. 2006. PMID: 16298174

6

Homocysteine exerts genotoxic and antioxidative effects in vitro.

Fink K, Brink A, Vienken J, Heidland A, Stopper H. Fink K, et al. Among authors: brink a. Toxicol In Vitro. 2007 Dec;21(8):1402-8. doi: 10.1016/j.tiv.2007.05.005. Epub 2007 May 18. Toxicol In Vitro. 2007. PMID: 17590309

7

Reduction of the genomic damage level in haemodialysis patients by folic acid and vitamin B12 supplementation.

Stopper H, Treutlein AT, Bahner U, Schupp N, Schmid U, Brink A, Perna A, Heidland A. Stopper H, et al. Among authors: brink a. Nephrol Dial Transplant. 2008 Oct;23(10):3272-9. doi: 10.1093/ndt/gfn254. Epub 2008 May 9. Nephrol Dial Transplant. 2008. PMID: 18469307

8

Genotoxicity Assessment of Drug Metabolites in the Context of MIST and Beyond.

Zeller A, Brigo A, Brink A, Guerard M, Lang D, Muster W, Runge F, Sutter A, Vock E, Wichard J, Schadt S. Zeller A, et al. Among authors: brink a. Chem Res Toxicol. 2020 Jan 21;33(1):10-19. doi: 10.1021/acs.chemrestox.9b00348. Epub 2020 Jan 9. Chem Res Toxicol. 2020. PMID: 31859487

9

Identification of GalNAc-Conjugated Antisense Oligonucleotide Metabolites Using an Untargeted and Generic Approach Based on High Resolution Mass Spectrometry.

Husser C, Brink A, Zell M, Müller MB, Koller E, Schadt S. Husser C, et al. Among authors: brink a. Anal Chem. 2017 Jun 20;89(12):6821-6826. doi: 10.1021/acs.analchem.7b01244. Epub 2017 May 25. Anal Chem. 2017. PMID: 28520401

10

Qualification of impurities based on metabolite data.

Weidolf L, Andersson T, Bercu JP, Brink A, Glowienke S, Harvey J, Hayes MA, Jacques P, Lu C, Manevski N, Muster W, Nudelman R, Ogilvie R, Ottosson J, Teasdale A, Trela B. Weidolf L, et al. Among authors: brink a. Regul Toxicol Pharmacol. 2020 Feb;110:104524. doi: 10.1016/j.yrtph.2019.104524. Epub 2019 Nov 14. Regul Toxicol Pharmacol. 2020. PMID: 31734179

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