Brookes PS - Search Results

1

Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity*.

Huwaimel BI, Bhakta M, Kulkarni CA, Milliken AS, Wang F, Peng A, Brookes PS, Trippier PC. Huwaimel BI, et al. Among authors: brookes ps. ChemMedChem. 2021 Apr 8;16(7):1143-1162. doi: 10.1002/cmdc.202000729. Epub 2021 Jan 26. ChemMedChem. 2021. PMID: 33331124 Free PMC article.

2

Synthesis and Antineoplastic Evaluation of Mitochondrial Complex II (Succinate Dehydrogenase) Inhibitors Derived from Atpenin A5.

Wang H, Huwaimel B, Verma K, Miller J, Germain TM, Kinarivala N, Pappas D, Brookes PS, Trippier PC. Wang H, et al. Among authors: brookes ps. ChemMedChem. 2017 Jul 6;12(13):1033-1044. doi: 10.1002/cmdc.201700196. Epub 2017 Jun 12. ChemMedChem. 2017. PMID: 28523727 Free PMC article.

3

Cellular Compartmentation and the Redox/Nonredox Functions of NAD.

Kulkarni CA, Brookes PS. Kulkarni CA, et al. Among authors: brookes ps. Antioxid Redox Signal. 2019 Sep 20;31(9):623-642. doi: 10.1089/ars.2018.7722. Epub 2019 Mar 26. Antioxid Redox Signal. 2019. PMID: 30784294 Free PMC article.

4

Amber alert: getting to the heart of succinate efflux in reperfusion injury.

Milliken AS, Brookes PS. Milliken AS, et al. Among authors: brookes ps. Cardiovasc Res. 2021 Mar 21;117(4):997-998. doi: 10.1093/cvr/cvaa216. Cardiovasc Res. 2021. PMID: 32666087 No abstract available.

5

ALKBH7 mediates necrosis via rewiring of glyoxal metabolism.

Kulkarni CA, Nadtochiy SM, Kennedy L, Zhang J, Chhim S, Alwaseem H, Murphy E, Fu D, Brookes PS. Kulkarni CA, et al. Among authors: brookes ps. Elife. 2020 Aug 14;9:e58573. doi: 10.7554/eLife.58573. Elife. 2020. PMID: 32795389 Free PMC article.

6

Acid enhancement of ROS generation by complex-I reverse electron transport is balanced by acid inhibition of complex-II: Relevance for tissue reperfusion injury.

Milliken AS, Kulkarni CA, Brookes PS. Milliken AS, et al. Among authors: brookes ps. Redox Biol. 2020 Oct;37:101733. doi: 10.1016/j.redox.2020.101733. Epub 2020 Sep 19. Redox Biol. 2020. PMID: 33007502 Free PMC article.

7

Inhibiting Succinate Release Worsens Cardiac Reperfusion Injury by Enhancing Mitochondrial Reactive Oxygen Species Generation.

Milliken AS, Nadtochiy SM, Brookes PS. Milliken AS, et al. Among authors: brookes ps. J Am Heart Assoc. 2022 Jul 5;11(13):e026135. doi: 10.1161/JAHA.122.026135. Epub 2022 Jun 29. J Am Heart Assoc. 2022. PMID: 35766275 Free PMC article.

8

The mitochondrial complex II and ATP-sensitive potassium channel interaction: quantitation of the channel in heart mitochondria.

Wojtovich AP, Nehrke KW, Brookes PS. Wojtovich AP, et al. Among authors: brookes ps. Acta Biochim Pol. 2010;57(4):431-4. Epub 2010 Nov 19. Acta Biochim Pol. 2010. PMID: 21103454 Free PMC article.

9

Mitochondrially targeted nitro-linoleate: a new tool for the study of cardioprotection.

Nadtochiy SM, Madukwe J, Hagen F, Brookes PS. Nadtochiy SM, et al. Among authors: brookes ps. Br J Pharmacol. 2014 Apr;171(8):2091-8. doi: 10.1111/bph.12405. Br J Pharmacol. 2014. PMID: 24102583 Free PMC article.

10

Physiological consequences of complex II inhibition for aging, disease, and the mKATP channel.

Wojtovich AP, Smith CO, Haynes CM, Nehrke KW, Brookes PS. Wojtovich AP, et al. Among authors: brookes ps. Biochim Biophys Acta. 2013 May;1827(5):598-611. doi: 10.1016/j.bbabio.2012.12.007. Epub 2013 Jan 2. Biochim Biophys Acta. 2013. PMID: 23291191 Free PMC article. Review.

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