Bruggeman SW - Search Results

1

In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis.

Gargiulo G, Cesaroni M, Serresi M, de Vries N, Hulsman D, Bruggeman SW, Lancini C, van Lohuizen M. Gargiulo G, et al. Among authors: bruggeman sw. Cancer Cell. 2013 May 13;23(5):660-76. doi: 10.1016/j.ccr.2013.03.030. Cancer Cell. 2013. PMID: 23680149 Free article.

2

Stem cells and cancer; the polycomb connection.

Valk-Lingbeek ME, Bruggeman SW, van Lohuizen M. Valk-Lingbeek ME, et al. Among authors: bruggeman sw. Cell. 2004 Aug 20;118(4):409-18. doi: 10.1016/j.cell.2004.08.005. Cell. 2004. PMID: 15315754 Free article. Review.

3

Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma.

Bruggeman SW, Hulsman D, Tanger E, Buckle T, Blom M, Zevenhoven J, van Tellingen O, van Lohuizen M. Bruggeman SW, et al. Cancer Cell. 2007 Oct;12(4):328-41. doi: 10.1016/j.ccr.2007.08.032. Cancer Cell. 2007. PMID: 17936558 Free article.

4

Bmi1 deficient neural stem cells have increased integrin dependent adhesion to self-secreted matrix.

Bruggeman SW, Hulsman D, van Lohuizen M. Bruggeman SW, et al. Biochim Biophys Acta. 2009 May;1790(5):351-60. doi: 10.1016/j.bbagen.2009.03.009. Epub 2009 Mar 16. Biochim Biophys Acta. 2009. PMID: 19298843

5

Rapid and robust transgenic high-grade glioma mouse models for therapy intervention studies.

de Vries NA, Bruggeman SW, Hulsman D, de Vries HI, Zevenhoven J, Buckle T, Hamans BC, Leenders WP, Beijnen JH, van Lohuizen M, Berns AJ, van Tellingen O. de Vries NA, et al. Among authors: bruggeman sw. Clin Cancer Res. 2010 Jul 1;16(13):3431-41. doi: 10.1158/1078-0432.CCR-09-3414. Epub 2010 May 14. Clin Cancer Res. 2010. PMID: 20472681 Free article.

6

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.

Bruggeman SW, Valk-Lingbeek ME, van der Stoop PP, Jacobs JJ, Kieboom K, Tanger E, Hulsman D, Leung C, Arsenijevic Y, Marino S, van Lohuizen M. Bruggeman SW, et al. Genes Dev. 2005 Jun 15;19(12):1438-43. doi: 10.1101/gad.1299305. Genes Dev. 2005. PMID: 15964995 Free PMC article.

7

Controlling stem cell proliferation: CKIs at work.

Bruggeman SW, van Lohuizen M. Bruggeman SW, et al. Cell Cycle. 2006 Jun;5(12):1281-5. doi: 10.4161/cc.5.12.2806. Epub 2006 Jun 15. Cell Cycle. 2006. PMID: 16760652

8

Emerging roles of Polycomb silencing in X-inactivation and stem cell maintenance.

Muyrers-Chen I, Hernández-Muñoz I, Lund AH, Valk-Lingbeek ME, van der Stoop P, Boutsma E, Tolhuis B, Bruggeman SW, Taghavi P, Verhoeven E, Hulsman D, Noback S, Tanger E, Theunissen H, van Lohuizen M. Muyrers-Chen I, et al. Among authors: bruggeman sw. Cold Spring Harb Symp Quant Biol. 2004;69:319-26. doi: 10.1101/sqb.2004.69.319. Cold Spring Harb Symp Quant Biol. 2004. PMID: 16117664 Review. No abstract available.

9

Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation.

Peric-Hupkes D, Meuleman W, Pagie L, Bruggeman SW, Solovei I, Brugman W, Gräf S, Flicek P, Kerkhoven RM, van Lohuizen M, Reinders M, Wessels L, van Steensel B. Peric-Hupkes D, et al. Among authors: bruggeman sw. Mol Cell. 2010 May 28;38(4):603-13. doi: 10.1016/j.molcel.2010.03.016. Mol Cell. 2010. PMID: 20513434 Free PMC article.

10

Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation.

Klauke K, Radulović V, Broekhuis M, Weersing E, Zwart E, Olthof S, Ritsema M, Bruggeman S, Wu X, Helin K, Bystrykh L, de Haan G. Klauke K, et al. Nat Cell Biol. 2013 Apr;15(4):353-62. doi: 10.1038/ncb2701. Epub 2013 Mar 17. Nat Cell Biol. 2013. PMID: 23502315

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