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Immunosuppression after sepsis: systemic inflammation and sepsis induce a loss of naïve T-cells but no enduring cell-autonomous defects in T-cell function.
Markwart R, Condotta SA, Requardt RP, Borken F, Schubert K, Weigel C, Bauer M, Griffith TS, Förster M, Brunkhorst FM, Badovinac VP, Rubio I. Markwart R, et al. Among authors: brunkhorst fm. PLoS One. 2014 Dec 26;9(12):e115094. doi: 10.1371/journal.pone.0115094. eCollection 2014. PLoS One. 2014. PMID: 25541945 Free PMC article.
Chronic Critical Illness from Sepsis Is Associated with an Enhanced TCR Response.
Borken F, Markwart R, Requardt RP, Schubert K, Spacek M, Verner M, Rückriem S, Scherag A, Oehmichen F, Brunkhorst FM, Rubio I. Borken F, et al. Among authors: brunkhorst fm. J Immunol. 2017 Jun 15;198(12):4781-4791. doi: 10.4049/jimmunol.1700142. Epub 2017 May 8. J Immunol. 2017. PMID: 28484052
Current gaps in sepsis immunology: new opportunities for translational research.
Rubio I, Osuchowski MF, Shankar-Hari M, Skirecki T, Winkler MS, Lachmann G, La Rosée P, Monneret G, Venet F, Bauer M, Brunkhorst FM, Kox M, Cavaillon JM, Uhle F, Weigand MA, Flohé SB, Wiersinga WJ, Martin-Fernandez M, Almansa R, Martin-Loeches I, Torres A, Giamarellos-Bourboulis EJ, Girardis M, Cossarizza A, Netea MG, van der Poll T, Scherag A, Meisel C, Schefold JC, Bermejo-Martín JF. Rubio I, et al. Among authors: brunkhorst fm. Lancet Infect Dis. 2019 Dec;19(12):e422-e436. doi: 10.1016/S1473-3099(19)30567-5. Epub 2019 Oct 17. Lancet Infect Dis. 2019. PMID: 31630991 Review.
Assessing efficacy of CytoSorb haemoadsorber for prevention of organ dysfunction in cardiac surgery patients with infective endocarditis: REMOVE-protocol for randomised controlled trial.
Diab M, Platzer S, Guenther A, Sponholz C, Scherag A, Lehmann T, Velichkov I, Hagel S, Bauer M, Brunkhorst FM, Doenst T. Diab M, et al. Among authors: brunkhorst fm. BMJ Open. 2020 Mar 30;10(3):e031912. doi: 10.1136/bmjopen-2019-031912. BMJ Open. 2020. PMID: 32234739 Free PMC article.
Use of IFNγ/IL10 Ratio for Stratification of Hydrocortisone Therapy in Patients With Septic Shock.
König R, Kolte A, Ahlers O, Oswald M, Krauss V, Roell D, Sommerfeld O, Dimopoulos G, Tsangaris I, Antoniadou E, Jaishankar N, Bogatsch H, Löffler M, Rödel M, Garcia-Moreno M, Tuchscherr L, Sprung CL, Singer M, Brunkhorst F, Oppert M, Gerlach H, Claus RA, Coldewey SM, Briegel J, Giamarellos-Bourboulis EJ, Keh D, Bauer M. König R, et al. Front Immunol. 2021 Mar 9;12:607217. doi: 10.3389/fimmu.2021.607217. eCollection 2021. Front Immunol. 2021. PMID: 33767693 Free PMC article.
The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity.
Osuchowski MF, Winkler MS, Skirecki T, Cajander S, Shankar-Hari M, Lachmann G, Monneret G, Venet F, Bauer M, Brunkhorst FM, Weis S, Garcia-Salido A, Kox M, Cavaillon JM, Uhle F, Weigand MA, Flohé SB, Wiersinga WJ, Almansa R, de la Fuente A, Martin-Loeches I, Meisel C, Spinetti T, Schefold JC, Cilloniz C, Torres A, Giamarellos-Bourboulis EJ, Ferrer R, Girardis M, Cossarizza A, Netea MG, van der Poll T, Bermejo-Martín JF, Rubio I. Osuchowski MF, et al. Among authors: brunkhorst fm. Lancet Respir Med. 2021 Jun;9(6):622-642. doi: 10.1016/S2213-2600(21)00218-6. Epub 2021 May 6. Lancet Respir Med. 2021. PMID: 33965003 Free PMC article. Review.
184 results