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The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus.
Karimi MM, Guo Y, Cui X, Pallikonda HA, Horková V, Wang YF, Gil SR, Rodriguez-Esteban G, Robles-Rebollo I, Bruno L, Georgieva R, Patel B, Elliott J, Dore MH, Dauphars D, Krangel MS, Lenhard B, Heyn H, Fisher AG, Štěpánek O, Merkenschlager M. Karimi MM, et al. Among authors: bruno l. Nat Commun. 2021 Jan 4;12(1):99. doi: 10.1038/s41467-020-20306-w. Nat Commun. 2021. PMID: 33397934 Free PMC article.
Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation.
Ferreirós-Vidal I, Carroll T, Taylor B, Terry A, Liang Z, Bruno L, Dharmalingam G, Khadayate S, Cobb BS, Smale ST, Spivakov M, Srivastava P, Petretto E, Fisher AG, Merkenschlager M. Ferreirós-Vidal I, et al. Among authors: bruno l. Blood. 2013 Mar 7;121(10):1769-82. doi: 10.1182/blood-2012-08-450114. Epub 2013 Jan 9. Blood. 2013. PMID: 23303821 Free article.
Selective deployment of transcription factor paralogs with submaximal strength facilitates gene regulation in the immune system.
Bruno L, Ramlall V, Studer RA, Sauer S, Bradley D, Dharmalingam G, Carroll T, Ghoneim M, Chopin M, Nutt SL, Elderkin S, Rueda DS, Fisher AG, Siggers T, Beltrao P, Merkenschlager M. Bruno L, et al. Nat Immunol. 2019 Oct;20(10):1372-1380. doi: 10.1038/s41590-019-0471-5. Epub 2019 Aug 26. Nat Immunol. 2019. PMID: 31451789 Free PMC article.
microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells.
Marcais A, Blevins R, Graumann J, Feytout A, Dharmalingam G, Carroll T, Amado IF, Bruno L, Lee K, Walzer T, Mann M, Freitas AA, Boothby M, Fisher AG, Merkenschlager M. Marcais A, et al. Among authors: bruno l. J Exp Med. 2014 Oct 20;211(11):2281-95. doi: 10.1084/jem.20132059. Epub 2014 Oct 13. J Exp Med. 2014. PMID: 25311506 Free PMC article.
Runx proteins regulate Foxp3 expression.
Bruno L, Mazzarella L, Hoogenkamp M, Hertweck A, Cobb BS, Sauer S, Hadjur S, Leleu M, Naoe Y, Telfer JC, Bonifer C, Taniuchi I, Fisher AG, Merkenschlager M. Bruno L, et al. J Exp Med. 2009 Oct 26;206(11):2329-37. doi: 10.1084/jem.20090226. Epub 2009 Oct 19. J Exp Med. 2009. PMID: 19841090 Free PMC article.
Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice.
Van de Pette M, Dimond A, Galvão AM, Millership SJ, To W, Prodani C, McNamara G, Bruno L, Sardini A, Webster Z, McGinty J, French PMW, Uren AG, Castillo-Fernandez J, Watkinson W, Ferguson-Smith AC, Merkenschlager M, John RM, Kelsey G, Fisher AG. Van de Pette M, et al. Among authors: bruno l. Nat Commun. 2022 May 5;13(1):2464. doi: 10.1038/s41467-022-30022-2. Nat Commun. 2022. PMID: 35513363 Free PMC article.
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.
Sauer S, Bruno L, Hertweck A, Finlay D, Leleu M, Spivakov M, Knight ZA, Cobb BS, Cantrell D, O'Connor E, Shokat KM, Fisher AG, Merkenschlager M. Sauer S, et al. Among authors: bruno l. Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7797-802. doi: 10.1073/pnas.0800928105. Epub 2008 May 28. Proc Natl Acad Sci U S A. 2008. PMID: 18509048 Free PMC article.
465 results