Bukhari SNA - Search Results

1

Novel tetrahydrocarbazole benzyl pyridine hybrids as potent and selective butryl cholinesterase inhibitors with neuroprotective and β-secretase inhibition activities.

Ghobadian R, Mahdavi M, Nadri H, Moradi A, Edraki N, Akbarzadeh T, Sharifzadeh M, Bukhari SNA, Amini M. Ghobadian R, et al. Among authors: bukhari sna. Eur J Med Chem. 2018 Jul 15;155:49-60. doi: 10.1016/j.ejmech.2018.05.031. Epub 2018 May 23. Eur J Med Chem. 2018. PMID: 29857276

2

Synthesis of α, β-unsaturated carbonyl based compounds as acetylcholinesterase and butyrylcholinesterase inhibitors: characterization, molecular modeling, QSAR studies and effect against amyloid β-induced cytotoxicity.

Bukhari SN, Jantan I, Masand VH, Mahajan DT, Sher M, Naeem-ul-Hassan M, Amjad MW. Bukhari SN, et al. Eur J Med Chem. 2014 Aug 18;83:355-65. doi: 10.1016/j.ejmech.2014.06.034. Epub 2014 Jun 17. Eur J Med Chem. 2014. PMID: 24980117

3

Biological evaluation of synthetic α,β-unsaturated carbonyl based cyclohexanone derivatives as neuroprotective novel inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.

Zha GF, Zhang CP, Qin HL, Jantan I, Sher M, Amjad MW, Hussain MA, Hussain Z, Bukhari SN. Zha GF, et al. Bioorg Med Chem. 2016 May 15;24(10):2352-9. doi: 10.1016/j.bmc.2016.04.015. Epub 2016 Apr 8. Bioorg Med Chem. 2016. PMID: 27083471

4

Synthesis, biological evaluation, docking study and ulcerogenicity profiling of some novel quinoline-2-carboxamides as dual COXs/LOX inhibitors endowed with anti-inflammatory activity.

Abdelrahman MH, Youssif BGM, Abdelgawad MA, Abdelazeem AH, Ibrahim HM, Moustafa AEGA, Treamblu L, Bukhari SNA. Abdelrahman MH, et al. Among authors: bukhari sna. Eur J Med Chem. 2017 Feb 15;127:972-985. doi: 10.1016/j.ejmech.2016.11.006. Epub 2016 Nov 5. Eur J Med Chem. 2017. PMID: 27837994

5

Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance.

Zha GF, Qin HL, Youssif BGM, Amjad MW, Raja MAG, Abdelazeem AH, Bukhari SNA. Zha GF, et al. Among authors: bukhari sna. Eur J Med Chem. 2017 Jul 28;135:34-48. doi: 10.1016/j.ejmech.2017.04.025. Epub 2017 Apr 14. Eur J Med Chem. 2017. PMID: 28431353

6

New racemic annulated pyrazolo[1,2-b]phthalazines as tacrine-like AChE inhibitors with potential use in Alzheimer's disease.

Jalili-Baleh L, Nadri H, Moradi A, Bukhari SNA, Shakibaie M, Jafari M, Golshani M, Homayouni Moghadam F, Firoozpour L, Asadipour A, Emami S, Khoobi M, Foroumadi A. Jalili-Baleh L, et al. Among authors: bukhari sna. Eur J Med Chem. 2017 Oct 20;139:280-289. doi: 10.1016/j.ejmech.2017.07.072. Epub 2017 Jul 31. Eur J Med Chem. 2017. PMID: 28803044

7

Discovery of a COX-2 selective inhibitor hit with anti-inflammatory activity and gastric ulcer protective effect.

Abdelgawad MA, Bakr RB, El-Gendy AO, Kamel GM, Azouz AA, Bukhari SNA. Abdelgawad MA, et al. Among authors: bukhari sna. Future Med Chem. 2017 Oct;9(16):1899-1912. doi: 10.4155/fmc-2017-0115. Epub 2017 Oct 27. Future Med Chem. 2017. PMID: 29076755

8

Recent Developments on Phenstatins as Potent Antimitotic Agents.

Chen X, Wang SM, Kumar GB, Bare GAL, Leng J, Bukhari SNA, Qin HL. Chen X, et al. Among authors: bukhari sna. Curr Med Chem. 2018;25(20):2329-2352. doi: 10.2174/0929867324666171106162048. Curr Med Chem. 2018. PMID: 29110592 Review.

9

Novel 1,2,4-triazole derivatives as potential anticancer agents: Design, synthesis, molecular docking and mechanistic studies.

El-Sherief HAM, Youssif BGM, Bukhari SNA, Abdel-Aziz M, Abdel-Rahman HM. El-Sherief HAM, et al. Among authors: bukhari sna. Bioorg Chem. 2018 Feb;76:314-325. doi: 10.1016/j.bioorg.2017.12.013. Epub 2017 Dec 5. Bioorg Chem. 2018. PMID: 29227915

10

Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino[1,2-a]indol-1(2H)-ones as potential anticancer agents effecting the reactive oxygen species production.

Youssif BGM, Abdelrahman MH, Abdelazeem AH, Abdelgawad MA, Ibrahim HM, Salem OIA, Mohamed MFA, Treambleau L, Bukhari SNA. Youssif BGM, et al. Among authors: bukhari sna. Eur J Med Chem. 2018 Feb 25;146:260-273. doi: 10.1016/j.ejmech.2018.01.042. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29407956

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