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A kinase-cGAS cascade to synthesize a therapeutic STING activator.
McIntosh JA, Liu Z, Andresen BM, Marzijarani NS, Moore JC, Marshall NM, Borra-Garske M, Obligacion JV, Fier PS, Peng F, Forstater JH, Winston MS, An C, Chang W, Lim J, Huffman MA, Miller SP, Tsay FR, Altman MD, Lesburg CA, Steinhuebel D, Trotter BW, Cumming JN, Northrup A, Bu X, Mann BF, Biba M, Hiraga K, Murphy GS, Kolev JN, Makarewicz A, Pan W, Farasat I, Bade RS, Stone K, Duan D, Alvizo O, Adpressa D, Guetschow E, Hoyt E, Regalado EL, Castro S, Rivera N, Smith JP, Wang F, Crespo A, Verma D, Axnanda S, Dance ZEX, Devine PN, Tschaen D, Canada KA, Bulger PG, Sherry BD, Truppo MD, Ruck RT, Campeau LC, Bennett DJ, Humphrey GR, Campos KR, Maddess ML. McIntosh JA, et al. Among authors: bulger pg. Nature. 2022 Mar;603(7901):439-444. doi: 10.1038/s41586-022-04422-9. Epub 2022 Mar 16. Nature. 2022. PMID: 35296845
Cascade reactions in total synthesis.
Nicolaou KC, Edmonds DJ, Bulger PG. Nicolaou KC, et al. Among authors: bulger pg. Angew Chem Int Ed Engl. 2006 Nov 6;45(43):7134-86. doi: 10.1002/anie.200601872. Angew Chem Int Ed Engl. 2006. PMID: 17075967 Review.
Metathesis reactions in total synthesis.
Nicolaou KC, Bulger PG, Sarlah D. Nicolaou KC, et al. Among authors: bulger pg. Angew Chem Int Ed Engl. 2005 Jul 18;44(29):4490-527. doi: 10.1002/anie.200500369. Angew Chem Int Ed Engl. 2005. PMID: 16003791
11 results