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GP130 activation induces myeloma and collaborates with MYC.
Dechow T, Steidle S, Götze KS, Rudelius M, Behnke K, Pechloff K, Kratzat S, Bullinger L, Fend F, Soberon V, Mitova N, Li Z, Thaler M, Bauer J, Pietschmann E, Albers C, Grundler R, Schmidt-Supprian M, Ruland J, Peschel C, Duyster J, Rose-John S, Bassermann F, Keller U. Dechow T, et al. Among authors: bullinger l. J Clin Invest. 2014 Dec;124(12):5263-74. doi: 10.1172/JCI69094. Epub 2014 Nov 10. J Clin Invest. 2014. PMID: 25384216 Free PMC article. Clinical Trial.
SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma.
Fernández-Sáiz V, Targosz BS, Lemeer S, Eichner R, Langer C, Bullinger L, Reiter C, Slotta-Huspenina J, Schroeder S, Knorn AM, Kurutz J, Peschel C, Pagano M, Kuster B, Bassermann F. Fernández-Sáiz V, et al. Among authors: bullinger l. Nat Cell Biol. 2013 Jan;15(1):72-81. doi: 10.1038/ncb2651. Nat Cell Biol. 2013. PMID: 23263282
CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.
Faber K, Bullinger L, Ragu C, Garding A, Mertens D, Miller C, Martin D, Walcher D, Döhner K, Döhner H, Claus R, Plass C, Sykes SM, Lane SW, Scholl C, Fröhling S. Faber K, et al. Among authors: bullinger l. J Clin Invest. 2013 Jan;123(1):299-314. doi: 10.1172/JCI64745. Epub 2012 Dec 3. J Clin Invest. 2013. PMID: 23202735 Free PMC article.
Genotype and Intensive Pretreatment Influence Outcome of Acute Myeloid Leukemia Patients Treated With Venetoclax in Combination With Hypomethylating Agents or Low-dose Cytarabine: "Real World" Data From Germany.
Braitsch K, Schmalbrock LK, Jung P, Bumeder I, Kiewe P, Hecker JS, Verbeek M, Westermann J, Bullinger L, Keller U, Bassermann F, Krönke J, Götze KS, Rieger K. Braitsch K, et al. Among authors: bullinger l. Hemasphere. 2022 Aug 9;6(9):e759. doi: 10.1097/HS9.0000000000000759. eCollection 2022 Sep. Hemasphere. 2022. PMID: 35966764 Free PMC article. No abstract available.
Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.
Ng YLD, Ramberger E, Bohl SR, Dolnik A, Steinebach C, Conrad T, Müller S, Popp O, Kull M, Haji M, Gütschow M, Döhner H, Walther W, Keller U, Bullinger L, Mertins P, Krönke J. Ng YLD, et al. Among authors: bullinger l. Nat Commun. 2022 Feb 23;13(1):1009. doi: 10.1038/s41467-022-28515-1. Nat Commun. 2022. PMID: 35197447 Free PMC article.
TET2 mutations in acute myeloid leukemia (AML): results from a comprehensive genetic and clinical analysis of the AML study group.
Gaidzik VI, Paschka P, Späth D, Habdank M, Köhne CH, Germing U, von Lilienfeld-Toal M, Held G, Horst HA, Haase D, Bentz M, Götze K, Döhner H, Schlenk RF, Bullinger L, Döhner K. Gaidzik VI, et al. Among authors: bullinger l. J Clin Oncol. 2012 Apr 20;30(12):1350-7. doi: 10.1200/JCO.2011.39.2886. Epub 2012 Mar 19. J Clin Oncol. 2012. PMID: 22430270 Clinical Trial.
Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis.
Sander S, Calado DP, Srinivasan L, Köchert K, Zhang B, Rosolowski M, Rodig SJ, Holzmann K, Stilgenbauer S, Siebert R, Bullinger L, Rajewsky K. Sander S, et al. Among authors: bullinger l. Cancer Cell. 2012 Aug 14;22(2):167-79. doi: 10.1016/j.ccr.2012.06.012. Cancer Cell. 2012. PMID: 22897848 Free PMC article.
IKZF1 expression is a prognostic marker in newly diagnosed standard-risk multiple myeloma treated with lenalidomide and intensive chemotherapy: a study of the German Myeloma Study Group (DSMM).
Krönke J, Kuchenbauer F, Kull M, Teleanu V, Bullinger L, Bunjes D, Greiner A, Kolmus S, Köpff S, Schreder M, Mügge LO, Straka C, Engelhardt M, Döhner H, Einsele H, Bassermann F, Bargou R, Knop S, Langer C. Krönke J, et al. Among authors: bullinger l. Leukemia. 2017 Jun;31(6):1363-1367. doi: 10.1038/leu.2016.384. Epub 2016 Dec 26. Leukemia. 2017. PMID: 28017969 Clinical Trial.
385 results