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Synaptopathy connects inflammation and neurodegeneration in multiple sclerosis.
Mandolesi G, Gentile A, Musella A, Fresegna D, De Vito F, Bullitta S, Sepman H, Marfia GA, Centonze D. Mandolesi G, et al. Among authors: bullitta s. Nat Rev Neurol. 2015 Dec;11(12):711-24. doi: 10.1038/nrneurol.2015.222. Epub 2015 Nov 20. Nat Rev Neurol. 2015. PMID: 26585978 Review.
Peripheral T cells from multiple sclerosis patients trigger synaptotoxic alterations in central neurons.
Gentile A, De Vito F, Fresegna D, Rizzo FR, Bullitta S, Guadalupi L, Vanni V, Buttari F, Stampanoni Bassi M, Leuti A, Chiurchiù V, Marfia GA, Mandolesi G, Centonze D, Musella A. Gentile A, et al. Among authors: bullitta s. Neuropathol Appl Neurobiol. 2020 Feb;46(2):160-170. doi: 10.1111/nan.12569. Epub 2019 Jun 17. Neuropathol Appl Neurobiol. 2020. PMID: 31125471
Siponimod (BAF312) prevents synaptic neurodegeneration in experimental multiple sclerosis.
Gentile A, Musella A, Bullitta S, Fresegna D, De Vito F, Fantozzi R, Piras E, Gargano F, Borsellino G, Battistini L, Schubart A, Mandolesi G, Centonze D. Gentile A, et al. Among authors: bullitta s. J Neuroinflammation. 2016 Aug 26;13(1):207. doi: 10.1186/s12974-016-0686-4. J Neuroinflammation. 2016. PMID: 27566665 Free PMC article.
miR-142-3p Is a Key Regulator of IL-1β-Dependent Synaptopathy in Neuroinflammation.
Mandolesi G, De Vito F, Musella A, Gentile A, Bullitta S, Fresegna D, Sepman H, Di Sanza C, Haji N, Mori F, Buttari F, Perlas E, Ciotti MT, Hornstein E, Bozzoni I, Presutti C, Centonze D. Mandolesi G, et al. Among authors: bullitta s. J Neurosci. 2017 Jan 18;37(3):546-561. doi: 10.1523/JNEUROSCI.0851-16.2016. J Neurosci. 2017. PMID: 28100738 Free PMC article.
Immunomodulatory Effects of Exercise in Experimental Multiple Sclerosis.
Gentile A, Musella A, De Vito F, Rizzo FR, Fresegna D, Bullitta S, Vanni V, Guadalupi L, Stampanoni Bassi M, Buttari F, Centonze D, Mandolesi G. Gentile A, et al. Among authors: bullitta s. Front Immunol. 2019 Sep 13;10:2197. doi: 10.3389/fimmu.2019.02197. eCollection 2019. Front Immunol. 2019. PMID: 31572399 Free PMC article. Review.
'Prototypical' proinflammatory cytokine (IL-1) in multiple sclerosis: role in pathogenesis and therapeutic targeting.
Musella A, Fresegna D, Rizzo FR, Gentile A, De Vito F, Caioli S, Guadalupi L, Bruno A, Dolcetti E, Buttari F, Bullitta S, Vanni V, Centonze D, Mandolesi G. Musella A, et al. Among authors: bullitta s. Expert Opin Ther Targets. 2020 Jan;24(1):37-46. doi: 10.1080/14728222.2020.1709823. Epub 2020 Jan 3. Expert Opin Ther Targets. 2020. PMID: 31899994 Review.
Central Modulation of Selective Sphingosine-1-Phosphate Receptor 1 Ameliorates Experimental Multiple Sclerosis.
Musella A, Gentile A, Guadalupi L, Rizzo FR, De Vito F, Fresegna D, Bruno A, Dolcetti E, Vanni V, Vitiello L, Bullitta S, Sanna K, Caioli S, Balletta S, Nencini M, Buttari F, Stampanoni Bassi M, Centonze D, Mandolesi G. Musella A, et al. Among authors: bullitta s. Cells. 2020 May 22;9(5):1290. doi: 10.3390/cells9051290. Cells. 2020. PMID: 32455907 Free PMC article.
38 results