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Increased formate overflow is a hallmark of oxidative cancer.
Meiser J, Schuster A, Pietzke M, Vande Voorde J, Athineos D, Oizel K, Burgos-Barragan G, Wit N, Dhayade S, Morton JP, Dornier E, Sumpton D, Mackay GM, Blyth K, Patel KJ, Niclou SP, Vazquez A. Meiser J, et al. Among authors: burgos barragan g. Nat Commun. 2018 Apr 10;9(1):1368. doi: 10.1038/s41467-018-03777-w. Nat Commun. 2018. PMID: 29636461 Free PMC article.
Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen.
Pontel LB, Rosado IV, Burgos-Barragan G, Garaycoechea JI, Yu R, Arends MJ, Chandrasekaran G, Broecker V, Wei W, Liu L, Swenberg JA, Crossan GP, Patel KJ. Pontel LB, et al. Among authors: burgos barragan g. Mol Cell. 2015 Oct 1;60(1):177-88. doi: 10.1016/j.molcel.2015.08.020. Epub 2015 Sep 24. Mol Cell. 2015. PMID: 26412304 Free PMC article.
Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.
Burgos-Barragan G, Wit N, Meiser J, Dingler FA, Pietzke M, Mulderrig L, Pontel LB, Rosado IV, Brewer TF, Cordell RL, Monks PS, Chang CJ, Vazquez A, Patel KJ. Burgos-Barragan G, et al. Nature. 2017 Aug 31;548(7669):549-554. doi: 10.1038/nature23481. Epub 2017 Aug 16. Nature. 2017. PMID: 28813411 Free PMC article.
Erratum: Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.
Burgos-Barragan G, Wit N, Meiser J, Dingler FA, Pietzke M, Mulderrig L, Pontel LB, Rosado IV, Brewer TF, Cordell RL, Monks PS, Chang CJ, Vazquez A, Patel KJ. Burgos-Barragan G, et al. Nature. 2017 Aug 31;548(7669):612. doi: 10.1038/nature23904. Epub 2017 Aug 23. Nature. 2017. PMID: 29411778 Free PMC article.
Amino acid dependent formaldehyde metabolism in mammals.
Pietzke M, Burgos-Barragan G, Wit N, Tait-Mulder J, Sumpton D, Mackay GM, Patel KJ, Vazquez A. Pietzke M, et al. Among authors: burgos barragan g. Commun Chem. 2020 Jun 16;3(1):78. doi: 10.1038/s42004-020-0324-z. Commun Chem. 2020. PMID: 36703413 Free PMC article.
Diet and Cancer Metabolism.
Locasale JW, Goncalves MD, Di Tano M, Burgos-Barragan G. Locasale JW, et al. Among authors: burgos barragan g. Cold Spring Harb Perspect Med. 2024 Apr 15:a041549. doi: 10.1101/cshperspect.a041549. Online ahead of print. Cold Spring Harb Perspect Med. 2024. PMID: 38621831