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2016 1
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2020 2
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Page 1
Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis.
Perry RJ, Zhang D, Guerra MT, Brill AL, Goedeke L, Nasiri AR, Rabin-Court A, Wang Y, Peng L, Dufour S, Zhang Y, Zhang XM, Butrico GM, Toussaint K, Nozaki Y, Cline GW, Petersen KF, Nathanson MH, Ehrlich BE, Shulman GI. Perry RJ, et al. Among authors: butrico gm. Nature. 2020 Mar;579(7798):279-283. doi: 10.1038/s41586-020-2074-6. Epub 2020 Mar 4. Nature. 2020. PMID: 32132708 Free PMC article.
Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo.
Madiraju AK, Qiu Y, Perry RJ, Rahimi Y, Zhang XM, Zhang D, Camporez JG, Cline GW, Butrico GM, Kemp BE, Casals G, Steinberg GR, Vatner DF, Petersen KF, Shulman GI. Madiraju AK, et al. Among authors: butrico gm. Nat Med. 2018 Sep;24(9):1384-1394. doi: 10.1038/s41591-018-0125-4. Epub 2018 Jul 23. Nat Med. 2018. PMID: 30038219 Free PMC article.
Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis.
LaMoia TE, Butrico GM, Kalpage HA, Goedeke L, Hubbard BT, Vatner DF, Gaspar RC, Zhang XM, Cline GW, Nakahara K, Woo S, Shimada A, Hüttemann M, Shulman GI. LaMoia TE, et al. Among authors: butrico gm. Proc Natl Acad Sci U S A. 2022 Mar 8;119(10):e2122287119. doi: 10.1073/pnas.2122287119. Epub 2022 Mar 1. Proc Natl Acad Sci U S A. 2022. PMID: 35238637 Free PMC article.
Metabolic control analysis of hepatic glycogen synthesis in vivo.
Nozaki Y, Petersen MC, Zhang D, Vatner DF, Perry RJ, Abulizi A, Haedersdal S, Zhang XM, Butrico GM, Samuel VT, Mason GF, Cline GW, Petersen KF, Rothman DL, Shulman GI. Nozaki Y, et al. Among authors: butrico gm. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):8166-8176. doi: 10.1073/pnas.1921694117. Epub 2020 Mar 18. Proc Natl Acad Sci U S A. 2020. PMID: 32188779 Free PMC article.
Reduced intestinal lipid absorption and body weight-independent improvements in insulin sensitivity in high-fat diet-fed Park2 knockout mice.
Costa DK, Huckestein BR, Edmunds LR, Petersen MC, Nasiri A, Butrico GM, Abulizi A, Harmon DB, Lu C, Mantell BS, Hartman DJ, Camporez JP, O'Doherty RM, Cline GW, Shulman GI, Jurczak MJ. Costa DK, et al. Among authors: butrico gm. Am J Physiol Endocrinol Metab. 2016 Jul 1;311(1):E105-16. doi: 10.1152/ajpendo.00042.2016. Epub 2016 May 10. Am J Physiol Endocrinol Metab. 2016. PMID: 27166280 Free PMC article.