The methylerythritol phosphate pathway is functionally active in all intraerythrocytic stages of Plasmodium falciparum.
Cassera MB, Gozzo FC, D'Alexandri FL, Merino EF, del Portillo HA, Peres VJ, Almeida IC, Eberlin MN, Wunderlich G, Wiesner J, Jomaa H, Kimura EA, Katzin AM.
Cassera MB, et al. Among authors: d alexandri fl.
J Biol Chem. 2004 Dec 10;279(50):51749-59. doi: 10.1074/jbc.M408360200. Epub 2004 Sep 27.
J Biol Chem. 2004.
PMID: 15452112
Free article.
Herein we report the first isolation and characterization of most downstream intermediates of the MEP pathway in the three intraerythrocytic stages of P. falciparum. These include, 1-deoxy-D-xylulose-5-phosphate, 2-C-methyl-D-erythritol-4-phosphate, 4-(cytidine-5-diphospho …
Herein we report the first isolation and characterization of most downstream intermediates of the MEP pathway in the three intraerythrocytic …