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Structural interactions between actin, tropomyosin, caldesmon and calcium binding protein and the regulation of smooth muscle thin filaments.
Marston S, Burton D, Copeland O, Fraser I, Gao Y, Hodgkinson J, Huber P, Levine B, el-Mezgueldi M, Notarianni G. Marston S, et al. Among authors: notarianni g. Acta Physiol Scand. 1998 Dec;164(4):401-14. doi: 10.1111/j.1365-201x.1998.tb10696.x. Acta Physiol Scand. 1998. PMID: 9887964 Review.
We have combined functional studies with expression and mutagenesis of caldesmon and with structural methods including X-ray crystalography of tropomyosin-caldesmon crystals, electron microscopy and helical reconstruction of actin-tropomyosin-caldesmon complexes and high resoluti …
We have combined functional studies with expression and mutagenesis of caldesmon and with structural methods including X-ray crystalography …
Innovating the Model for Student Pharmacists to Increase Access to Hepatitis C Testing (Project IMPACT).
Januszka J, Notarianni V, Devenny E, Harris E. Januszka J, et al. Among authors: notarianni v. J Am Pharm Assoc (2003). 2023 Jul-Aug;63(4):1217-1221. doi: 10.1016/j.japh.2023.04.001. Epub 2023 Apr 8. J Am Pharm Assoc (2003). 2023. PMID: 37037394
BACKGROUND: Previous initiatives have described the feasibility of conducting point-of-care testing (POCT) for hepatitis C virus (HCV) within community pharmacies. Limited research has been conducted to evaluate the role of student pharmacists and technicians in providing …
BACKGROUND: Previous initiatives have described the feasibility of conducting point-of-care testing (POCT) for hepatitis C virus (HCV …
Global activation of oncogenic pathways underlies therapy resistance in diffuse midline glioma.
Georgescu MM, Islam MZ, Li Y, Circu ML, Traylor J, Notarianni CM, Kline CN, Burns DK. Georgescu MM, et al. Among authors: notarianni cm. Acta Neuropathol Commun. 2020 Jul 17;8(1):111. doi: 10.1186/s40478-020-00992-9. Acta Neuropathol Commun. 2020. PMID: 32680567 Free PMC article.
Activation of oncogenic pathways resulted from combined upregulation of N-MYC, SOX2, p65/p50 NF-kappaB and STAT3 transcription factors, EGFR, FGFR2, PDGFRalpha/beta receptor tyrosine kinases, and downregulation of PHLPP1/2, PTEN and p16/INK4A tumor suppressors. Upregulation of SM …
Activation of oncogenic pathways resulted from combined upregulation of N-MYC, SOX2, p65/p50 NF-kappaB and STAT3 transcription factors, EGFR …
Incorporation of cultured embryonic cells into transgenic and chimeric, porcine fetuses.
Notarianni E, Laurie S, NG A, Sathasivam K. Notarianni E, et al. Int J Dev Biol. 1997 Jun;41(3):537-40. Int J Dev Biol. 1997. PMID: 9240573 Free article.
In the first instance, chimerism was revealed in one fetus by the presence of the transgene, as detected by Southern blotting; and in the second instance, in that and another fetus by the presence of supernumerary alleles for the class II major histocompatibility locus, SLA-DQB* …
In the first instance, chimerism was revealed in one fetus by the presence of the transgene, as detected by Southern blotting; and in the se …
Comparison of the survival and tolerability of radioembolization in elderly vs. younger patients with unresectable hepatocellular carcinoma.
Golfieri R, Bilbao JI, Carpanese L, Cianni R, Gasparini D, Ezziddin S, Paprottka PM, Fiore F, Cappelli A, Rodriguez M, Ettorre GM, Saltarelli A, Geatti O, Ahmadzadehfar H, Haug AR, Izzo F, Giampalma E, Sangro B, Pizzi G, Notarianni E, Vit A, Wilhelm K, Jakobs TF, Lastoria S; European Network on Radioembolization with Yttrium-90 Microspheres (ENRY) study collaborators. Golfieri R, et al. Among authors: notarianni e. J Hepatol. 2013 Oct;59(4):753-61. doi: 10.1016/j.jhep.2013.05.025. Epub 2013 May 23. J Hepatol. 2013. PMID: 23707371 Clinical Trial.
Many elderly and younger patients alike had multinodular, BCLC stage C disease, invading both lobes (p = 0.648). Elderly patients had a lower tumor burden, a smaller median target liver volume (p = 0.016) and appeared more likely to receive segmental treatment (p = 0.054). …
Many elderly and younger patients alike had multinodular, BCLC stage C disease, invading both lobes (p = 0.648). Elderly patients had …
A novel Ca2+ binding protein associated with caldesmon in Ca2+-regulated smooth muscle thin filaments: evidence for a structurally altered form of calmodulin.
Notarianni G, Gusev N, Lafitte D, Hill TJ, Cooper HS, Derrick PJ, Marston SB. Notarianni G, et al. J Muscle Res Cell Motil. 2000;21(6):537-49. doi: 10.1023/a:1026589704750. J Muscle Res Cell Motil. 2000. PMID: 11206132
Thin filament activation of myosin MgATPase is Ca2+-regulated but thin filaments assembled from smooth muscle actin, tropomyosin and caldesmon plus brain or aorta calmodulin are not Ca2+-regulated at 25 degrees C/50 mM KCl. We isolated the Ca2+-binding protein (CaBP) from …
Thin filament activation of myosin MgATPase is Ca2+-regulated but thin filaments assembled from smooth muscle actin, tropomyosin and caldesm …
[Cystadenoma of the seminal vesicles. A case report].
D'Erme M, Notarianni E, Misiti A, Santarelli M, Tombolini V. D'Erme M, et al. Among authors: notarianni e. Radiol Med. 1996 Mar;91(3):322-4. Radiol Med. 1996. PMID: 8628954 Review. Italian. No abstract available.