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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 2
1978 2
1979 3
1980 1
1981 4
1982 2
1983 3
1984 5
1985 10
1986 4
1987 12
1988 11
1989 20
1990 18
1991 29
1992 31
1993 33
1994 37
1995 46
1996 45
1997 73
1998 63
1999 90
2000 94
2001 97
2002 137
2003 164
2004 203
2005 256
2006 280
2007 344
2008 434
2009 479
2010 567
2011 632
2012 789
2013 838
2014 1007
2015 1191
2016 1249
2017 1399
2018 1637
2019 1877
2020 2032
2021 2159
2022 2281
2023 2284
2024 1024

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21,305 results

Results by year

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Page 1
Metabolic rewiring controlled by c-Fos governs cartilage integrity in osteoarthritis.
Matsuoka K, Bakiri L, Bilban M, Toegel S, Haschemi A, Yuan H, Kasper M, Windhager R, Wagner EF. Matsuoka K, et al. Among authors: yuan h. Ann Rheum Dis. 2023 Sep;82(9):1227-1239. doi: 10.1136/ard-2023-224002. Epub 2023 Jun 21. Ann Rheum Dis. 2023. PMID: 37344157 Free PMC article.
Cartilage-specific c-Fos knockout (c-Fos(deltaCh)) mice were generated by crossing c-fos(fl/fl) to Col2a1-CreERT mice. ...Compared with c-Fos(WT) mice, c-Fos(deltaCh) mice exhibited exacerbated DMM-induced cartilage destruction. ...
Cartilage-specific c-Fos knockout (c-Fos(deltaCh)) mice were generated by crossing c-fos(fl/fl) to Col2a1-CreERT mice. …
Bicaudal-C protein, a potential antidepressant target.
Han Q, Jiang J, Yuan Y, Tang B, Zhang J. Han Q, et al. Among authors: yuan y. Neuroreport. 2021 Nov 2;32(16):1293-1298. doi: 10.1097/WNR.0000000000001729. Neuroreport. 2021. PMID: 34554934 Review.
Genome-wide association study identified that Bicaudal-C protein was associated with depression. The expression of Bicaudal-C increased in depression patients, also increased expression of Bicaudal-C induces the behavior of depression. ...Therefore, Bicaudal- …
Genome-wide association study identified that Bicaudal-C protein was associated with depression. The expression of Bicaudal-C …
WSB1 regulates c-Myc expression through beta-catenin signaling and forms a feedforward circuit.
Gao X, You J, Gong Y, Yuan M, Zhu H, Fang L, Zhu H, Ying M, He Q, Yang B, Cao J. Gao X, et al. Among authors: yuan m. Acta Pharm Sin B. 2022 Mar;12(3):1225-1239. doi: 10.1016/j.apsb.2021.10.021. Epub 2021 Oct 26. Acta Pharm Sin B. 2022. PMID: 35530152 Free PMC article.
Given that there is no effective way to directly inhibit c-Myc, c-Myc targeting strategies hold great potential for cancer therapy. In this study, we found that WSB1, which has a highly positive correlation with c-Myc in 10 cancer cell lines and clinical samp …
Given that there is no effective way to directly inhibit c-Myc, c-Myc targeting strategies hold great potential for cancer the …
Stereoretentive Post-Translational Protein Editing.
Fu XP, Yuan Y, Jha A, Levin N, Giltrap AM, Ren J, Mamalis D, Mohammed S, Davis BG. Fu XP, et al. Among authors: yuan y. ACS Cent Sci. 2023 Feb 24;9(3):405-416. doi: 10.1021/acscentsci.2c00991. eCollection 2023 Mar 22. ACS Cent Sci. 2023. PMID: 36968537 Free PMC article.
Current approaches that allow the creation of constitutionally native side chains via C-C bond formation, using off-protein carbon-centered C. radicals added to unnatural amino acid radical acceptor (SOMOphile, singly occupied molecular orbital (SOMO)) "tags" …
Current approaches that allow the creation of constitutionally native side chains via C-C bond formation, using off-protein ca …
Intramolecular (directed) electrophilic C-H borylation.
Iqbal SA, Pahl J, Yuan K, Ingleson MJ. Iqbal SA, et al. Among authors: yuan k. Chem Soc Rev. 2020 Jun 4. doi: 10.1039/c9cs00763f. Online ahead of print. Chem Soc Rev. 2020. PMID: 32495755 Review.
The intramolecular C-H borylation of (hetero)arenes and alkenes using electrophilic boranes is a powerful transition metal free methodology for forming C-B bonds. These C-H borylation reactions are preceded by intermolecular bond (both dative and covalent) fo …
The intramolecular C-H borylation of (hetero)arenes and alkenes using electrophilic boranes is a powerful transition metal free metho …
The role of tryptophan in Chlamydia trachomatis persistence.
Wang L, Hou Y, Yuan H, Chen H. Wang L, et al. Among authors: yuan h. Front Cell Infect Microbiol. 2022 Aug 2;12:931653. doi: 10.3389/fcimb.2022.931653. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35982780 Free PMC article. Review.
Importantly, the underlying mechanisms of C. trachomatis infection are not fully understood. C. trachomatis has the ability to adapt to immune response and persist within host epithelial cells. ...In this review, we discuss the characteristics of chlamydial infectio …
Importantly, the underlying mechanisms of C. trachomatis infection are not fully understood. C. trachomatis has the ability to …
Trichothecenes: structure-toxic activity relationships.
Wu Q, Dohnal V, Kuca K, Yuan Z. Wu Q, et al. Among authors: yuan z. Curr Drug Metab. 2013 Jul;14(6):641-60. doi: 10.2174/1389200211314060002. Curr Drug Metab. 2013. PMID: 23869809 Review.
Trichothecenes toxicity increases when a macrocyclic ring exists between the C-4 and C-15. At C-8 position, an oxygenated substitution at C-8 is essential for trichothecene toxicity, indicating a decrease in the toxicity if substituent change from isov …
Trichothecenes toxicity increases when a macrocyclic ring exists between the C-4 and C-15. At C-8 position, an oxygenat …
Revealing dual roles of g-C(3)N(4) in Chlorella vulgaris cultivation.
Feng Q, Sun Y, Li A, Lin X, Lu T, Ding D, Shi M, Sun Y, Yuan Y. Feng Q, et al. Among authors: yuan y. J Hazard Mater. 2022 Feb 15;424(Pt C):127639. doi: 10.1016/j.jhazmat.2021.127639. Epub 2021 Oct 30. J Hazard Mater. 2022. PMID: 34750001
However, a controversial understanding regarding effect of g-C(3)N(4) on growth of microalgae still exists. Accordingly, Chlorella vulgaris were cultured in 0-250 mg/L of g-C(3)N(4) with biomass named as C-0, C-50, C-100, C-150, C- …
However, a controversial understanding regarding effect of g-C(3)N(4) on growth of microalgae still exists. Accordingly, Chlorella vu …
Expanding the Phenotypic and Genotypic Spectrum of ARFGEF1-Related Neurodevelopmental Disorder.
Xu L, Zhou Y, Ren X, Xu C, Ren R, Yan X, Li X, Yang H, Xu X, Guo X, Sheng G, Hua Y, Yuan Z, Wang S, Gu W, Sun D, Gao F. Xu L, et al. Among authors: yuan z. Front Mol Neurosci. 2022 Jun 17;15:862096. doi: 10.3389/fnmol.2022.862096. eCollection 2022. Front Mol Neurosci. 2022. PMID: 35782386 Free PMC article.
In this study, five novel heterozygous ARFGEF1 variants were identified in five unrelated pediatric patients with neurodevelopmental disorders, including one missense change (c.3539T>G), two canonical splice site variants (c.917-1G>T, c.2850+2T>A), a …
In this study, five novel heterozygous ARFGEF1 variants were identified in five unrelated pediatric patients with neurodevelopmental disorde …
Hepatitis C Virus-Associated Cancers.
Yi Z, Yuan Z. Yi Z, et al. Among authors: yuan z. Adv Exp Med Biol. 2017;1018:129-146. doi: 10.1007/978-981-10-5765-6_8. Adv Exp Med Biol. 2017. PMID: 29052135 Review.
Most hepatitis C virus (HCV) infection results in persistent infection. Significant portion of chronic HCV-infected patients develop hepatocellular carcinoma (HCC). Chronic hepatitis C is also associated with extrahepatic manifestations, including cryoglobulinemia, …
Most hepatitis C virus (HCV) infection results in persistent infection. Significant portion of chronic HCV-infected patients develop …
21,305 results
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