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Page 1
Did you mean c h u[Author] (1 results)?
Efficient heterologous expression of cytochrome P450 enzymes in microorganisms for the biosynthesis of natural products.
Hu B, Zhao X, Wang E, Zhou J, Li J, Chen J, Du G. Hu B, et al. Crit Rev Biotechnol. 2023 Mar;43(2):227-241. doi: 10.1080/07388551.2022.2029344. Epub 2022 Feb 6. Crit Rev Biotechnol. 2023. PMID: 35129020 Review.
P450s are heme-containing enzymes that use molecular oxygen and the hydride donor NAD(P)H (coupled via enzymic redox partners) to catalyze the insertion of oxygen into C-H bonds in a regio- and stereo-selective manner, effecting hydroxylation and several other react …
P450s are heme-containing enzymes that use molecular oxygen and the hydride donor NAD(P)H (coupled via enzymic redox partners) to catalyze t …
Palladium-catalyzed C(sp3)-H nitrooxylation of masked alcohols.
Xue Y, Zhou RB, Luo J, Hu BC, Liu ZQ, Jiang C. Xue Y, et al. Among authors: hu bc. Org Biomol Chem. 2022 Dec 21;21(1):75-79. doi: 10.1039/d2ob01919a. Org Biomol Chem. 2022. PMID: 36448655
An 8-formylquinoline-derived oxime is installed as an exo-type directing group for sp(3) C-H activation and selectfluor acts as the oxidant. The reaction tolerates a variety of functional groups and shows good selectivity for beta-C-H nitrooxylation of …
An 8-formylquinoline-derived oxime is installed as an exo-type directing group for sp(3) C-H activation and selectfluor acts a …
Metal-Catalyzed Decarboxylative C-H Functionalization.
Wei Y, Hu P, Zhang M, Su W. Wei Y, et al. Among authors: hu p. Chem Rev. 2017 Jul 12;117(13):8864-8907. doi: 10.1021/acs.chemrev.6b00516. Epub 2017 Mar 7. Chem Rev. 2017. PMID: 28266216
C-H bond activation and decarboxylation are two significant processes in organic synthesis. The combination of these processes provides a novel synthetic strategy, that is, decarboxylative C-H bond functionalization. Considerable attention has been foc
C-H bond activation and decarboxylation are two significant processes in organic synthesis. The combination of these processes
Functionalization of C-H Bonds by Photoredox Catalysis.
Qin Q, Jiang H, Hu Z, Ren D, Yu S. Qin Q, et al. Among authors: hu z. Chem Rec. 2017 Aug;17(8):754-774. doi: 10.1002/tcr.201600125. Epub 2017 Jan 11. Chem Rec. 2017. PMID: 28074599 Review.
Visible-light photoredox catalysis has been successfully used in the functionalization of inert C-H bonds including C(sp(2) )-H bonds of arenes and C(sp(3) )-H bonds of aliphatic compounds over the past decade. ...
Visible-light photoredox catalysis has been successfully used in the functionalization of inert C-H bonds including C(sp(2) )- …
Genomic heterogeneity as a barrier to precision oncology in urothelial cancer.
Clinton TN, Chen Z, Wise H, Lenis AT, Chavan S, Donoghue MTA, Almassi N, Chu CE, Dason S, Rao P, Rodrigues JA, Vasani NB, Ridouani F, Rosenberg JE, Bajorin DF, Teo MY, Bochner BH, Berger MF, Ostrovnaya I, Pietzak EJ, Iyer G, Gao SP, Hu W, Al-Ahmadie HA, Solit DB. Clinton TN, et al. Among authors: hu w. Cell Rep. 2022 Dec 20;41(12):111859. doi: 10.1016/j.celrep.2022.111859. Cell Rep. 2022. PMID: 36543146 Free PMC article.
Boron-Assisted Cobalt-Catalyzed C-H Methylation Using CO(2) and H(2).
Shi Q, Hu H, Du M, Sun Y, Li Y, Li Y. Shi Q, et al. Among authors: hu h. Org Lett. 2023 Oct 6;25(39):7100-7104. doi: 10.1021/acs.orglett.3c02406. Epub 2023 Sep 28. Org Lett. 2023. PMID: 37767977
C-H methylation of heteroarenes (e.g., indoles, pyrroles, etc.) is frequently applied in the synthesis of drug/biorelated compounds. ...This system based on the use of non-noble metal catalysts features an environmentally benign alternative for C-H met
C-H methylation of heteroarenes (e.g., indoles, pyrroles, etc.) is frequently applied in the synthesis of drug/biorelated comp
Pd-Catalyzed Asymmetric Oxidative C-H/C-H Cross-Coupling Reaction between Ferrocenes and Azoles.
Cao F, Wang Y, Feng P, Hu J, Yang Y, Zhang H. Cao F, et al. Among authors: hu j. J Org Chem. 2023 May 5;88(9):5752-5759. doi: 10.1021/acs.joc.3c00212. Epub 2023 Apr 21. J Org Chem. 2023. PMID: 37083480
The asymmetric C-H bond functionalization reaction is one of the most efficient and straightforward methods for the synthesis of optically active molecules. Herein, our work discovered a Pd-catalyzed asymmetric oxidative C-H/C-H cross-cou …
The asymmetric C-H bond functionalization reaction is one of the most efficient and straightforward methods for the synthesis …
Modular, stereocontrolled Cβ-H/Cα-C activation of alkyl carboxylic acids.
Shang M, Feu KS, Vantourout JC, Barton LM, Osswald HL, Kato N, Gagaring K, McNamara CW, Chen G, Hu L, Ni S, Fernández-Canelas P, Chen M, Merchant RR, Qin T, Schreiber SL, Melillo B, Yu JQ, Baran PS. Shang M, et al. Among authors: hu l. Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):8721-8727. doi: 10.1073/pnas.1903048116. Epub 2019 Apr 17. Proc Natl Acad Sci U S A. 2019. PMID: 30996125 Free PMC article.
The union of two powerful transformations, directed C-H activation and decarboxylative cross-coupling, for the enantioselective synthesis of vicinally functionalized alkyl, carbocyclic, and heterocyclic compounds is described. ...
The union of two powerful transformations, directed C-H activation and decarboxylative cross-coupling, for the enantioselectiv …
753 results