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Assessment of Protein Binding of 5-Hydroxythalidomide Bioactivated in Humanized Mice with Human P450 3A-Chromosome or Hepatocytes by Two-Dimensional Electrophoresis/Accelerator Mass Spectrometry.
Yamazaki H, Suemizu H, Kazuki Y, Oofusa K, Kuribayashi S, Shimizu M, Ninomiya S, Horie T, Shibata N, Guengerich FP. Yamazaki H, et al. Chem Res Toxicol. 2016 Aug 15;29(8):1279-81. doi: 10.1021/acs.chemrestox.6b00210. Epub 2016 Jul 29. Chem Res Toxicol. 2016. PMID: 27464947 Free PMC article.
Human cytochrome P450 27C1 catalyzes 3,4-desaturation of retinoids.
Kramlinger VM, Nagy LD, Fujiwara R, Johnson KM, Phan TT, Xiao Y, Enright JM, Toomey MB, Corbo JC, Guengerich FP. Kramlinger VM, et al. FEBS Lett. 2016 May;590(9):1304-12. doi: 10.1002/1873-3468.12167. Epub 2016 Apr 17. FEBS Lett. 2016. PMID: 27059013 Free PMC article.
118 results