CA129925/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

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Subject: CA129925/CA/NCI NIH HHS/United States[Grants and - PubMed

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Divalent ions attenuate DNA synthesis by human DNA polymerase α by changing the structure of the template/primer or by perturbing the polymerase reaction.

Zhang Y, Baranovskiy AG, Tahirov ET, Tahirov TH, Pavlov YI. Zhang Y, et al. DNA Repair (Amst). 2016 Jul;43:24-33. doi: 10.1016/j.dnarep.2016.05.017. Epub 2016 May 12. DNA Repair (Amst). 2016. PMID: 27235627 Free PMC article.

Insight into the Human DNA Primase Interaction with Template-Primer.

Baranovskiy AG, Zhang Y, Suwa Y, Gu J, Babayeva ND, Pavlov YI, Tahirov TH. Baranovskiy AG, et al. J Biol Chem. 2016 Feb 26;291(9):4793-802. doi: 10.1074/jbc.M115.704064. Epub 2015 Dec 28. J Biol Chem. 2016. PMID: 26710848 Free PMC article.

Crystal structure of the human primase.

Baranovskiy AG, Zhang Y, Suwa Y, Babayeva ND, Gu J, Pavlov YI, Tahirov TH. Baranovskiy AG, et al. J Biol Chem. 2015 Feb 27;290(9):5635-46. doi: 10.1074/jbc.M114.624742. Epub 2014 Dec 30. J Biol Chem. 2015. PMID: 25550159 Free PMC article.

Structural basis for inhibition of DNA replication by aphidicolin.

Baranovskiy AG, Babayeva ND, Suwa Y, Gu J, Pavlov YI, Tahirov TH. Baranovskiy AG, et al. Nucleic Acids Res. 2014 Dec 16;42(22):14013-21. doi: 10.1093/nar/gku1209. Epub 2014 Nov 27. Nucleic Acids Res. 2014. PMID: 25429975 Free PMC article.

The C-terminal domain of the DNA polymerase catalytic subunit regulates the primase and polymerase activities of the human DNA polymerase α-primase complex.

Zhang Y, Baranovskiy AG, Tahirov TH, Pavlov YI. Zhang Y, et al. J Biol Chem. 2014 Aug 8;289(32):22021-34. doi: 10.1074/jbc.M114.570333. Epub 2014 Jun 24. J Biol Chem. 2014. PMID: 24962573 Free PMC article.

A novel variant of DNA polymerase ζ, Rev3ΔC, highlights differential regulation of Pol32 as a subunit of polymerase δ versus ζ in Saccharomyces cerevisiae.

Siebler HM, Lada AG, Baranovskiy AG, Tahirov TH, Pavlov YI. Siebler HM, et al. DNA Repair (Amst). 2014 Dec;24:138-149. doi: 10.1016/j.dnarep.2014.04.013. Epub 2014 May 10. DNA Repair (Amst). 2014. PMID: 24819597 Free PMC article.

Genome-wide mutation avalanches induced in diploid yeast cells by a base analog or an APOBEC deaminase.

Lada AG, Stepchenkova EI, Waisertreiger IS, Noskov VN, Dhar A, Eudy JD, Boissy RJ, Hirano M, Rogozin IB, Pavlov YI. Lada AG, et al. PLoS Genet. 2013;9(9):e1003736. doi: 10.1371/journal.pgen.1003736. Epub 2013 Sep 5. PLoS Genet. 2013. PMID: 24039593 Free PMC article.

ITPA (inosine triphosphate pyrophosphatase): from surveillance of nucleotide pools to human disease and pharmacogenetics.

Simone PD, Pavlov YI, Borgstahl GEO. Simone PD, et al. Mutat Res. 2013 Oct-Dec;753(2):131-146. doi: 10.1016/j.mrrev.2013.08.001. Epub 2013 Aug 19. Mutat Res. 2013. PMID: 23969025 Free PMC article. Review.

The human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic core.

Simone PD, Struble LR, Kellezi A, Brown CA, Grabow CE, Khutsishvili I, Marky LA, Pavlov YI, Borgstahl GE. Simone PD, et al. J Struct Biol. 2013 Jun;182(3):197-208. doi: 10.1016/j.jsb.2013.03.007. Epub 2013 Mar 23. J Struct Biol. 2013. PMID: 23528839 Free PMC article.

AID/APOBEC cytosine deaminase induces genome-wide kataegis.

Lada AG, Dhar A, Boissy RJ, Hirano M, Rubel AA, Rogozin IB, Pavlov YI. Lada AG, et al. Biol Direct. 2012 Dec 18;7:47; discussion 47. doi: 10.1186/1745-6150-7-47. Biol Direct. 2012. PMID: 23249472 Free PMC article.

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