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2011 2
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Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified.
Breysse DH, Boone RM, Long CM, Merrill ME, Schaupp CM, White CC, Kavanagh TJ, Schmidt EE, Merrill GF. Breysse DH, et al. Drug Metab Dispos. 2020 Mar;48(3):187-197. doi: 10.1124/dmd.119.089326. Epub 2020 Jan 18. Drug Metab Dispos. 2020. PMID: 31955137 Free PMC article.
TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy.
McLoughlin MR, Orlicky DJ, Prigge JR, Krishna P, Talago EA, Cavigli IR, Eriksson S, Miller CG, Kundert JA, Sayin VI, Sabol RA, Heinemann J, Brandenberger LO, Iverson SV, Bothner B, Papagiannakopoulos T, Shearn CT, Arnér ESJ, Schmidt EE. McLoughlin MR, et al. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11408-11417. doi: 10.1073/pnas.1903244116. Epub 2019 May 16. Proc Natl Acad Sci U S A. 2019. PMID: 31097586 Free PMC article.
NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.
Chio IIC, Jafarnejad SM, Ponz-Sarvise M, Park Y, Rivera K, Palm W, Wilson J, Sangar V, Hao Y, Öhlund D, Wright K, Filippini D, Lee EJ, Da Silva B, Schoepfer C, Wilkinson JE, Buscaglia JM, DeNicola GM, Tiriac H, Hammell M, Crawford HC, Schmidt EE, Thompson CB, Pappin DJ, Sonenberg N, Tuveson DA. Chio IIC, et al. Cell. 2016 Aug 11;166(4):963-976. doi: 10.1016/j.cell.2016.06.056. Epub 2016 Jul 28. Cell. 2016. PMID: 27477511 Free PMC article.