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Ancestral SARS-CoV-2-specific T cells cross-recognize the Omicron variant.
Gao Y, Cai C, Grifoni A, Müller TR, Niessl J, Olofsson A, Humbert M, Hansson L, Österborg A, Bergman P, Chen P, Olsson A, Sandberg JK, Weiskopf D, Price DA, Ljunggren HG, Karlsson AC, Sette A, Aleman S, Buggert M. Gao Y, et al. Among authors: cai c. Nat Med. 2022 Mar;28(3):472-476. doi: 10.1038/s41591-022-01700-x. Epub 2022 Jan 14. Nat Med. 2022. PMID: 35042228 Free PMC article.
Immunodeficiency syndromes differentially impact the functional profile of SARS-CoV-2-specific T cells elicited by mRNA vaccination.
Gao Y, Cai C, Wullimann D, Niessl J, Rivera-Ballesteros O, Chen P, Lange J, Cuapio A, Blennow O, Hansson L, Mielke S, Nowak P, Vesterbacka J, Akber M, Perez-Potti A, Sekine T, Müller TR, Boulouis C, Kammann T, Parrot T, Muvva JR, Sobkowiak M, Healy K, Bogdanovic G, Muschiol S, Söderdahl G, Österborg A, Hellgren F, Grifoni A, Weiskopf D, Sette A, Loré K, Sällberg Chen M, Ljungman P, Sandberg JK, Smith CIE, Bergman P, Ljunggren HG, Aleman S, Buggert M. Gao Y, et al. Among authors: cai c. Immunity. 2022 Sep 13;55(9):1732-1746.e5. doi: 10.1016/j.immuni.2022.07.005. Epub 2022 Jul 19. Immunity. 2022. PMID: 35961317 Free PMC article.
Identification of human progenitors of exhausted CD8+ T cells associated with elevated IFN-γ response in early phase of viral infection.
Cai C, Samir J, Pirozyan MR, Adikari TN, Gupta M, Leung P, Hughes B, Van der Byl W, Rizzetto S, Elthala A, Keoshkerian E, Palgen JL, Peters T, Nguyen THO, Louie R, Kedzierska K, Gaudieri S, Bull RA, Lloyd AR, Luciani F. Cai C, et al. Nat Commun. 2022 Dec 7;13(1):7543. doi: 10.1038/s41467-022-35281-7. Nat Commun. 2022. PMID: 36477661 Free PMC article.
Functional SARS-CoV-2 cross-reactive CD4+ T cells established in early childhood decline with age.
Humbert M, Olofsson A, Wullimann D, Niessl J, Hodcroft EB, Cai C, Gao Y, Sohlberg E, Dyrdak R, Mikaeloff F, Neogi U, Albert J, Malmberg KJ, Lund-Johansen F, Aleman S, Björkhem-Bergman L, Jenmalm MC, Ljunggren HG, Buggert M, Karlsson AC. Humbert M, et al. Among authors: cai c. Proc Natl Acad Sci U S A. 2023 Mar 21;120(12):e2220320120. doi: 10.1073/pnas.2220320120. Epub 2023 Mar 14. Proc Natl Acad Sci U S A. 2023. PMID: 36917669 Free PMC article.
Additive effects of booster mRNA vaccination and SARS-CoV-2 Omicron infection on T cell immunity across immunocompromised states.
Müller TR, Sekine T, Trubach D, Niessl J, Chen P, Bergman P, Blennow O, Hansson L, Mielke S, Nowak P, Vesterbacka J, Akber M, Olofsson A, Amaya Hernandez SP, Gao Y, Cai C, Söderdahl G, Smith CIE, Österborg A, Loré K, Sällberg Chen M, Ljungman P, Ljunggren HG, Karlsson AC, Saini SK, Aleman S, Buggert M. Müller TR, et al. Among authors: cai c. Sci Transl Med. 2023 Jul 12;15(704):eadg9452. doi: 10.1126/scitranslmed.adg9452. Epub 2023 Jul 12. Sci Transl Med. 2023. PMID: 37437015 Free PMC article.
SARS-CoV-2 vaccination enhances the effector qualities of spike-specific T cells induced by COVID-19.
Cai C, Gao Y, Adamo S, Rivera-Ballesteros O, Hansson L, Österborg A, Bergman P, Sandberg JK, Ljunggren HG, Björkström NK, Strålin K, Llewellyn-Lacey S, Price DA, Qin C, Grifoni A, Weiskopf D, Wherry EJ, Sette A, Aleman S, Buggert M. Cai C, et al. Sci Immunol. 2023 Dec 8;8(90):eadh0687. doi: 10.1126/sciimmunol.adh0687. Epub 2023 Dec 8. Sci Immunol. 2023. PMID: 38064569 Free PMC article.
CAR+ and CAR- T cells share a differentiation trajectory into an NK-like subset after CD19 CAR T cell infusion in patients with B cell malignancies.
Louie RHY, Cai C, Samir J, Singh M, Deveson IW, Ferguson JM, Amos TG, McGuire HM, Gowrishankar K, Adikari T, Balderas R, Bonomi M, Ruella M, Bishop D, Gottlieb D, Blyth E, Micklethwaite K, Luciani F. Louie RHY, et al. Among authors: cai c. Nat Commun. 2023 Nov 27;14(1):7767. doi: 10.1038/s41467-023-43656-7. Nat Commun. 2023. PMID: 38012187 Free PMC article.
Single-Cell Transcriptome Analysis of T Cells.
Van Der Byl W, Rizzetto S, Samir J, Cai C, Eltahla AA, Luciani F. Van Der Byl W, et al. Among authors: cai c. Methods Mol Biol. 2019;2048:155-205. doi: 10.1007/978-1-4939-9728-2_16. Methods Mol Biol. 2019. PMID: 31396939
5,039 results