Reaction of trichloroethylene oxide with proteins and dna: instability of adducts and modulation of functions.
Cai H, Guengerich FP.
Cai H, et al.
Chem Res Toxicol. 2001 Jan;14(1):54-61. doi: 10.1021/tx000185n.
Chem Res Toxicol. 2001.
PMID: 11170508
We previously analyzed N(6)-acyllysine adducts formed from the reaction of TCE oxide with proteins [Cai, H., and Guengerich, F. P. (2000) Chem. Res. Toxicol. 13, 327-335]; however, we had been unable to measure ester adducts under the prolonged conditions of proteol …
We previously analyzed N(6)-acyllysine adducts formed from the reaction of TCE oxide with proteins [Cai, H., and Guengerich, F …