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SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors.
Roth L, Srivastava S, Lindzen M, Sas-Chen A, Sheffer M, Lauriola M, Enuka Y, Noronha A, Mancini M, Lavi S, Tarcic G, Pines G, Nevo N, Heyman O, Ziv T, Rueda OM, Gnocchi D, Pikarsky E, Admon A, Caldas C, Yarden Y. Roth L, et al. Among authors: caldas c. Sci Signal. 2018 Jan 30;11(515):eaan0949. doi: 10.1126/scisignal.aan0949. Sci Signal. 2018. PMID: 29382783
ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium.
Holland DG, Burleigh A, Git A, Goldgraben MA, Perez-Mancera PA, Chin SF, Hurtado A, Bruna A, Ali HR, Greenwood W, Dunning MJ, Samarajiwa S, Menon S, Rueda OM, Lynch AG, McKinney S, Ellis IO, Eaves CJ, Carroll JS, Curtis C, Aparicio S, Caldas C. Holland DG, et al. Among authors: caldas c. EMBO Mol Med. 2011 Mar;3(3):167-80. doi: 10.1002/emmm.201100122. Epub 2011 Feb 18. EMBO Mol Med. 2011. PMID: 21337521 Free PMC article.
Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor.
Mohammed H, D'Santos C, Serandour AA, Ali HR, Brown GD, Atkins A, Rueda OM, Holmes KA, Theodorou V, Robinson JL, Zwart W, Saadi A, Ross-Innes CS, Chin SF, Menon S, Stingl J, Palmieri C, Caldas C, Carroll JS. Mohammed H, et al. Among authors: caldas c. Cell Rep. 2013 Feb 21;3(2):342-9. doi: 10.1016/j.celrep.2013.01.010. Epub 2013 Feb 9. Cell Rep. 2013. PMID: 23403292 Free PMC article.
Finding common regions of alteration in copy number data.
Rueda OM, Diaz-Uriarte R, Caldas C. Rueda OM, et al. Among authors: caldas c. Methods Mol Biol. 2013;973:339-53. doi: 10.1007/978-1-62703-281-0_21. Methods Mol Biol. 2013. PMID: 23412800 Review.
Analysis of circulating tumor DNA to monitor metastatic breast cancer.
Dawson SJ, Tsui DW, Murtaza M, Biggs H, Rueda OM, Chin SF, Dunning MJ, Gale D, Forshew T, Mahler-Araujo B, Rajan S, Humphray S, Becq J, Halsall D, Wallis M, Bentley D, Caldas C, Rosenfeld N. Dawson SJ, et al. Among authors: caldas c. N Engl J Med. 2013 Mar 28;368(13):1199-209. doi: 10.1056/NEJMoa1213261. Epub 2013 Mar 13. N Engl J Med. 2013. PMID: 23484797 Free article.
Master regulators of FGFR2 signalling and breast cancer risk.
Fletcher MN, Castro MA, Wang X, de Santiago I, O'Reilly M, Chin SF, Rueda OM, Caldas C, Ponder BA, Markowetz F, Meyer KB. Fletcher MN, et al. Among authors: caldas c. Nat Commun. 2013;4:2464. doi: 10.1038/ncomms3464. Nat Commun. 2013. PMID: 24043118 Free PMC article.
689 results