Camire RM - Search Results

1

A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia.

Ivanciu L, Toso R, Margaritis P, Pavani G, Kim H, Schlachterman A, Liu JH, Clerin V, Pittman DD, Rose-Miranda R, Shields KM, Erbe DV, Tobin JF, Arruda VR, Camire RM. Ivanciu L, et al. Among authors: camire rm. Nat Biotechnol. 2011 Oct 23;29(11):1028-33. doi: 10.1038/nbt.1995. Nat Biotechnol. 2011. PMID: 22020385 Free PMC article.

2

Structure/function analyses of recombinant variants of human factor Xa: factor Xa incorporation into prothrombinase on the thrombin-activated platelet surface is not mimicked by synthetic phospholipid vesicles.

Larson PJ, Camire RM, Wong D, Fasano NC, Monroe DM, Tracy PB, High KA. Larson PJ, et al. Among authors: camire rm. Biochemistry. 1998 Apr 7;37(14):5029-38. doi: 10.1021/bi972428p. Biochemistry. 1998. PMID: 9538022

3

Posttranslational modifications of recombinant myotube-synthesized human factor IX.

Arruda VR, Hagstrom JN, Deitch J, Heiman-Patterson T, Camire RM, Chu K, Fields PA, Herzog RW, Couto LB, Larson PJ, High KA. Arruda VR, et al. Among authors: camire rm. Blood. 2001 Jan 1;97(1):130-8. doi: 10.1182/blood.v97.1.130. Blood. 2001. PMID: 11133752 Free article.

4

Factor VII mutant V154G models a zymogen-like form of factor VIIa.

Toso R, Bernardi F, Tidd T, Pinotti M, Camire RM, Marchetti G, High KA, Pollak ES. Toso R, et al. Among authors: camire rm. Biochem J. 2003 Feb 1;369(Pt 3):563-71. doi: 10.1042/BJ20020888. Biochem J. 2003. PMID: 12358603 Free PMC article.

5

Removal of B-domain sequences from factor V rather than specific proteolysis underlies the mechanism by which cofactor function is realized.

Toso R, Camire RM. Toso R, et al. Among authors: camire rm. J Biol Chem. 2004 May 14;279(20):21643-50. doi: 10.1074/jbc.M402107200. Epub 2004 Mar 5. J Biol Chem. 2004. PMID: 15004010 Free article.

6

Novel therapeutic approach for hemophilia using gene delivery of an engineered secreted activated Factor VII.

Margaritis P, Arruda VR, Aljamali M, Camire RM, Schlachterman A, High KA. Margaritis P, et al. Among authors: camire rm. J Clin Invest. 2004 Apr;113(7):1025-31. doi: 10.1172/JCI20106. J Clin Invest. 2004. PMID: 15057309 Free PMC article.

7

Factor V Leiden improves in vivo hemostasis in murine hemophilia models.

Schlachterman A, Schuettrumpf J, Liu JH, Furlan Freguia C, Toso R, Poncz M, Camire RM, Arruda VR. Schlachterman A, et al. Among authors: camire rm. J Thromb Haemost. 2005 Dec;3(12):2730-7. doi: 10.1111/j.1538-7836.2005.01639.x. J Thromb Haemost. 2005. PMID: 16359510 Free article.

8

Role of Hirudin-like factor Va heavy chain sequences in prothrombinase function.

Toso R, Camire RM. Toso R, et al. Among authors: camire rm. J Biol Chem. 2006 Mar 31;281(13):8773-9. doi: 10.1074/jbc.M511419200. Epub 2006 Jan 23. J Biol Chem. 2006. PMID: 16431918 Free article.

9

Inhibitory sequences within the B-domain stabilize circulating factor V in an inactive state.

Zhu H, Toso R, Camire RM. Zhu H, et al. Among authors: camire rm. J Biol Chem. 2007 May 18;282(20):15033-9. doi: 10.1074/jbc.M701315200. Epub 2007 Mar 26. J Biol Chem. 2007. PMID: 17387173 Free article.

10

The enhancing effects of the light chain on heavy chain secretion in split delivery of factor VIII gene.

Chen L, Zhu F, Li J, Lu H, Jiang H, Sarkar R, Arruda VR, Wang J, Zhao J, Pierce GF, Ding Q, Wang X, Wang H, Pipe SW, Liu XQ, Xiao X, Camire RM, Xiao W. Chen L, et al. Among authors: camire rm. Mol Ther. 2007 Oct;15(10):1856-62. doi: 10.1038/sj.mt.6300268. Epub 2007 Jul 24. Mol Ther. 2007. PMID: 17653101 Free PMC article.

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