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Page 1
Oncogenic Hijacking of the PIN1 Signaling Network.
Zannini A, Rustighi A, Campaner E, Del Sal G. Zannini A, et al. Among authors: campaner e. Front Oncol. 2019 Feb 25;9:94. doi: 10.3389/fonc.2019.00094. eCollection 2019. Front Oncol. 2019. PMID: 30873382 Free PMC article. Review.
PIN1 in breast development and cancer: a clinical perspective.
Rustighi A, Zannini A, Campaner E, Ciani Y, Piazza S, Del Sal G. Rustighi A, et al. Among authors: campaner e. Cell Death Differ. 2017 Feb;24(2):200-211. doi: 10.1038/cdd.2016.122. Epub 2016 Nov 11. Cell Death Differ. 2017. PMID: 27834957 Free PMC article. Review.
The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress.
Napoletano F, Ferrari Bravo G, Voto IAP, Santin A, Celora L, Campaner E, Dezi C, Bertossi A, Valentino E, Santorsola M, Rustighi A, Fajner V, Maspero E, Ansaloni F, Cancila V, Valenti CF, Santo M, Artimagnella OB, Finaurini S, Gioia U, Polo S, Sanges R, Tripodo C, Mallamaci A, Gustincich S, d'Adda di Fagagna F, Mantovani F, Specchia V, Del Sal G. Napoletano F, et al. Among authors: campaner e. Cell Rep. 2021 Sep 14;36(11):109694. doi: 10.1016/j.celrep.2021.109694. Cell Rep. 2021. PMID: 34525372 Free article.
Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome.
Capaci V, Bascetta L, Fantuz M, Beznoussenko GV, Sommaggio R, Cancila V, Bisso A, Campaner E, Mironov AA, Wiśniewski JR, Ulloa Severino L, Scaini D, Bossi F, Lees J, Alon N, Brunga L, Malkin D, Piazza S, Collavin L, Rosato A, Bicciato S, Tripodo C, Mantovani F, Del Sal G. Capaci V, et al. Among authors: campaner e. Nat Commun. 2020 Aug 7;11(1):3945. doi: 10.1038/s41467-020-17596-5. Nat Commun. 2020. PMID: 32770028 Free PMC article.
Breast Cancer Organoids Model Patient-Specific Response to Drug Treatment.
Campaner E, Zannini A, Santorsola M, Bonazza D, Bottin C, Cancila V, Tripodo C, Bortul M, Zanconati F, Schoeftner S, Del Sal G. Campaner E, et al. Cancers (Basel). 2020 Dec 21;12(12):3869. doi: 10.3390/cancers12123869. Cancers (Basel). 2020. PMID: 33371412 Free PMC article.
A covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action.
Campaner E, Rustighi A, Zannini A, Cristiani A, Piazza S, Ciani Y, Kalid O, Golan G, Baloglu E, Shacham S, Valsasina B, Cucchi U, Pippione AC, Lolli ML, Giabbai B, Storici P, Carloni P, Rossetti G, Benvenuti F, Bello E, D'Incalci M, Cappuzzello E, Rosato A, Del Sal G. Campaner E, et al. Nat Commun. 2017 Jun 9;8:15772. doi: 10.1038/ncomms15772. Nat Commun. 2017. PMID: 28598431 Free PMC article.