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Page 1
Uncovering interactions between mycobacterial respiratory complexes to target drug-resistant Mycobacterium tuberculosis.
Front Cell Infect Microbiol. 2022 Aug 24;12:980844. doi: 10.3389/fcimb.2022.980844. eCollection 2022.
Front Cell Infect Microbiol. 2022.
PMID: 36093195
Free PMC article.
Review.
Two for the price of one: Attacking the energetic-metabolic hub of mycobacteria to produce new chemotherapeutic agents.
Hards K, Adolph C, Harold LK, McNeil MB, Cheung CY, Jinich A, Rhee KY, Cook GM.
Hards K, et al. Among authors: adolph c.
Prog Biophys Mol Biol. 2020 May;152:35-44. doi: 10.1016/j.pbiomolbio.2019.11.003. Epub 2019 Nov 13.
Prog Biophys Mol Biol. 2020.
PMID: 31733221
Review.
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A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis.
Adolph C, Cheung CY, McNeil MB, Jowsey WJ, Williams ZC, Hards K, Harold LK, Aboelela A, Bujaroski RS, Buckley BJ, Tyndall JDA, Li Z, Langer JD, Preiss L, Meier T, Steyn AJC, Rhee KY, Berney M, Kelso MJ, Cook GM.
Adolph C, et al.
Cell Chem Biol. 2024 Apr 18;31(4):683-698.e7. doi: 10.1016/j.chembiol.2023.12.002. Epub 2023 Dec 26.
Cell Chem Biol. 2024.
PMID: 38151019
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Impaired Succinate Oxidation Prevents Growth and Influences Drug Susceptibility in Mycobacterium tuberculosis.
Adolph C, McNeil MB, Cook GM.
Adolph C, et al.
mBio. 2022 Aug 30;13(4):e0167222. doi: 10.1128/mbio.01672-22. Epub 2022 Jul 20.
mBio. 2022.
PMID: 35856639
Free PMC article.
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An amiloride derivative is active against the F1Fo-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis.
Hards K, Cheung CY, Waller N, Adolph C, Keighley L, Tee ZS, Harold LK, Menorca A, Bujaroski RS, Buckley BJ, Tyndall JDA, McNeil MB, Rhee KY, Opel-Reading HK, Krause K, Preiss L, Langer JD, Meier T, Hasenoehrl EJ, Berney M, Kelso MJ, Cook GM.
Hards K, et al. Among authors: adolph c.
Commun Biol. 2022 Feb 24;5(1):166. doi: 10.1038/s42003-022-03110-8.
Commun Biol. 2022.
PMID: 35210534
Free PMC article.
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