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Page 1
Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages.
Rowton M, Perez-Cervantes C, Hur S, Jacobs-Li J, Lu E, Deng N, Guzzetta A, Hoffmann AD, Stocker M, Steimle JD, Lazarevic S, Oubaha S, Yang XH, Kim C, Yu S, Eckart H, Koska M, Hanson E, Chan SSK, Garry DJ, Kyba M, Basu A, Ikegami K, Pott S, Moskowitz IP. Rowton M, et al. Among authors: perez cervantes c. Dev Cell. 2022 Sep 26;57(18):2181-2203.e9. doi: 10.1016/j.devcel.2022.08.009. Epub 2022 Sep 14. Dev Cell. 2022. PMID: 36108627 Free PMC article.
Tbx5 maintains atrial identity by regulating an atrial enhancer network.
Sweat ME, Cao Y, Zhang X, Burnicka-Turek O, Perez-Cervantes C, Akerberg BN, Ma Q, Wakimoto H, Gorham JM, Song MK, Trembley MA, Wang P, Lu F, Gianeselli M, Prondzynski M, Bortolin RH, Seidman JG, Seidman CE, Moskowitz IP, Pu WT. Sweat ME, et al. Among authors: perez cervantes c. bioRxiv [Preprint]. 2023 Apr 22:2023.04.21.537535. doi: 10.1101/2023.04.21.537535. bioRxiv. 2023. PMID: 37131696 Free PMC article. Updated. Preprint.
A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network.
Broman MT, Nadadur RD, Perez-Cervantes C, Burnicka-Turek O, Lazarevic S, Gams A, Laforest B, Steimle JD, Iddir S, Wang Z, Smith L, Mazurek SR, Olivey HE, Zhou P, Gadek M, Shen KM, Khan Z, Theisen JWM, Yang XH, Ikegami K, Efimov IR, Pu WT, Weber CR, McNally EM, Svensson EC, Moskowitz IP. Broman MT, et al. Among authors: perez cervantes c. Circulation. 2024 Apr 9;149(15):1205-1230. doi: 10.1161/CIRCULATIONAHA.123.066804. Epub 2024 Jan 8. Circulation. 2024. PMID: 38189150
Tbx5 maintains atrial identity in post-natal cardiomyocytes by regulating an atrial-specific enhancer network.
Sweat ME, Cao Y, Zhang X, Burnicka-Turek O, Perez-Cervantes C, Arulsamy K, Lu F, Keating EM, Akerberg BN, Ma Q, Wakimoto H, Gorham JM, Hill LD, Kyoung Song M, Trembley MA, Wang P, Gianeselli M, Prondzynski M, Bortolin RH, Bezzerides VJ, Chen K, Seidman JG, Seidman CE, Moskowitz IP, Pu WT. Sweat ME, et al. Among authors: perez cervantes c. Nat Cardiovasc Res. 2023 Oct;2(10):881-898. doi: 10.1038/s44161-023-00334-7. Epub 2023 Oct 12. Nat Cardiovasc Res. 2023. PMID: 38344303 Free PMC article.
Identification of direct transcriptional targets of NFATC2 that promote β cell proliferation.
Simonett SP, Shin S, Herring JA, Bacher R, Smith LA, Dong C, Rabaglia ME, Stapleton DS, Schueler KL, Choi J, Bernstein MN, Turkewitz DR, Perez-Cervantes C, Spaeth J, Stein R, Tessem JS, Kendziorski C, Keleş S, Moskowitz IP, Keller MP, Attie AD. Simonett SP, et al. Among authors: perez cervantes c. J Clin Invest. 2021 Nov 1;131(21):e144833. doi: 10.1172/JCI144833. J Clin Invest. 2021. PMID: 34491912 Free PMC article.
Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm.
Yang XH, Nadadur RD, Hilvering CR, Bianchi V, Werner M, Mazurek SR, Gadek M, Shen KM, Goldman JA, Tyan L, Bekeny J, Hall JM, Lee N, Perez-Cervantes C, Burnicka-Turek O, Poss KD, Weber CR, de Laat W, Ruthenburg AJ, Moskowitz IP. Yang XH, et al. Among authors: perez cervantes c. Elife. 2017 Dec 27;6:e31683. doi: 10.7554/eLife.31683. Elife. 2017. PMID: 29280435 Free PMC article.
Variants in WFS1 and Other Mendelian Deafness Genes Are Associated with Cisplatin-Associated Ototoxicity.
Wheeler HE, Gamazon ER, Frisina RD, Perez-Cervantes C, El Charif O, Mapes B, Fossa SD, Feldman DR, Hamilton RJ, Vaughn DJ, Beard CJ, Fung C, Kollmannsberger C, Kim J, Mushiroda T, Kubo M, Ardeshir-Rouhani-Fard S, Einhorn LH, Cox NJ, Dolan ME, Travis LB. Wheeler HE, et al. Among authors: perez cervantes c. Clin Cancer Res. 2017 Jul 1;23(13):3325-3333. doi: 10.1158/1078-0432.CCR-16-2809. Epub 2016 Dec 30. Clin Cancer Res. 2017. PMID: 28039263 Free PMC article.