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V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a.
EMBO Mol Med. 2010 Nov;2(11):458-71. doi: 10.1002/emmm.201000099.
EMBO Mol Med. 2010.
PMID: 20941790
Free PMC article.
Mouse models for BRAF-induced cancers.
Pritchard C, Carragher L, Aldridge V, Giblett S, Jin H, Foster C, Andreadi C, Kamata T.
Pritchard C, et al.
Biochem Soc Trans. 2007 Nov;35(Pt 5):1329-33. doi: 10.1042/BST0351329.
Biochem Soc Trans. 2007.
PMID: 17956344
Free PMC article.
Review.
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CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation.
Noble C, Mercer K, Hussain J, Carragher L, Giblett S, Hayward R, Patterson C, Marais R, Pritchard CA.
Noble C, et al.
Mol Cell. 2008 Sep 26;31(6):862-72. doi: 10.1016/j.molcel.2008.08.026.
Mol Cell. 2008.
PMID: 18922468
Free PMC article.
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