Carrell RW - Search Results

1

Inhibitory conformation of the reactive loop of alpha 1-antitrypsin.

Elliott PR, Lomas DA, Carrell RW, Abrahams JP. Elliott PR, et al. Among authors: carrell rw. Nat Struct Biol. 1996 Aug;3(8):676-81. doi: 10.1038/nsb0896-676. Nat Struct Biol. 1996. PMID: 8756325

2

6-mer peptide selectively anneals to a pathogenic serpin conformation and blocks polymerization. Implications for the prevention of Z alpha(1)-antitrypsin-related cirrhosis.

Mahadeva R, Dafforn TR, Carrell RW, Lomas DA. Mahadeva R, et al. Among authors: carrell rw. J Biol Chem. 2002 Mar 1;277(9):6771-4. doi: 10.1074/jbc.C100722200. Epub 2001 Dec 28. J Biol Chem. 2002. PMID: 11773044 Free article.

3

Alpha1-antitrypsin deficiency--a model for conformational diseases.

Carrell RW, Lomas DA. Carrell RW, et al. N Engl J Med. 2002 Jan 3;346(1):45-53. doi: 10.1056/NEJMra010772. N Engl J Med. 2002. PMID: 11778003 Review. No abstract available.

4

Serpinopathies and the conformational dementias.

Lomas DA, Carrell RW. Lomas DA, et al. Among authors: carrell rw. Nat Rev Genet. 2002 Oct;3(10):759-68. doi: 10.1038/nrg907. Nat Rev Genet. 2002. PMID: 12360234 Review.

5

Structure of beta-antithrombin and the effect of glycosylation on antithrombin's heparin affinity and activity.

McCoy AJ, Pei XY, Skinner R, Abrahams JP, Carrell RW. McCoy AJ, et al. Among authors: carrell rw. J Mol Biol. 2003 Feb 21;326(3):823-33. doi: 10.1016/s0022-2836(02)01382-7. J Mol Biol. 2003. PMID: 12581643

6

alpha 1-Antitrypsin Mmalton (Phe52-deleted) forms loop-sheet polymers in vivo. Evidence for the C sheet mechanism of polymerization.

Lomas DA, Elliott PR, Sidhar SK, Foreman RC, Finch JT, Cox DW, Whisstock JC, Carrell RW. Lomas DA, et al. Among authors: carrell rw. J Biol Chem. 1995 Jul 14;270(28):16864-70. doi: 10.1074/jbc.270.28.16864. J Biol Chem. 1995. PMID: 7622502 Free article.

7

Preparation and characterization of latent alpha 1-antitrypsin.

Lomas DA, Elliott PR, Chang WS, Wardell MR, Carrell RW. Lomas DA, et al. Among authors: carrell rw. J Biol Chem. 1995 Mar 10;270(10):5282-8. doi: 10.1074/jbc.270.10.5282. J Biol Chem. 1995. PMID: 7890640 Free article.

8

Conformational changes in serpins and the mechanism of alpha 1-antitrypsin deficiency.

Carrell RW, Whisstock J, Lomas DA. Carrell RW, et al. Am J Respir Crit Care Med. 1994 Dec;150(6 Pt 2):S171-5. doi: 10.1164/ajrccm/150.6_Pt_2.S171. Am J Respir Crit Care Med. 1994. PMID: 7952655 Review.

9

A protein structural approach to the solution of biological problems: alpha 1-antitrypsin as a recent example.

Lomas DA, Carrell RW. Lomas DA, et al. Among authors: carrell rw. Am J Physiol. 1993 Sep;265(3 Pt 1):L211-9. doi: 10.1152/ajplung.1993.265.3.L211. Am J Physiol. 1993. PMID: 8214081 Review.

10

Alpha 1-antitrypsin Siiyama (Ser53-->Phe). Further evidence for intracellular loop-sheet polymerization.

Lomas DA, Finch JT, Seyama K, Nukiwa T, Carrell RW. Lomas DA, et al. Among authors: carrell rw. J Biol Chem. 1993 Jul 25;268(21):15333-5. J Biol Chem. 1993. PMID: 8340361 Free article.

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