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Context-Dependent Signaling of CXC Chemokine Receptor 4 and Atypical Chemokine Receptor 3.
Heuninck J, Perpiñá Viciano C, Işbilir A, Caspar B, Capoferri D, Briddon SJ, Durroux T, Hill SJ, Lohse MJ, Milligan G, Pin JP, Hoffmann C. Heuninck J, et al. Among authors: caspar b. Mol Pharmacol. 2019 Dec;96(6):778-793. doi: 10.1124/mol.118.115477. Epub 2019 May 15. Mol Pharmacol. 2019. PMID: 31092552 Free article. Review.
Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists.
Adlere I, Sun S, Zarca A, Roumen L, Gozelle M, Viciano CP, Caspar B, Arimont M, Bebelman JP, Briddon SJ, Hoffmann C, Hill SJ, Smit MJ, Vischer HF, Wijtmans M, de Graaf C, de Esch IJP, Leurs R. Adlere I, et al. Among authors: caspar b. Eur J Med Chem. 2019 Jan 15;162:631-649. doi: 10.1016/j.ejmech.2018.10.060. Epub 2018 Oct 30. Eur J Med Chem. 2019. PMID: 30476826
Modulators of CXCR4 and CXCR7/ACKR3 Function.
Adlere I, Caspar B, Arimont M, Dekkers S, Visser K, Stuijt J, de Graaf C, Stocks M, Kellam B, Briddon S, Wijtmans M, de Esch I, Hill S, Leurs R. Adlere I, et al. Among authors: caspar b. Mol Pharmacol. 2019 Dec;96(6):737-752. doi: 10.1124/mol.119.117663. Epub 2019 Sep 23. Mol Pharmacol. 2019. PMID: 31548340 Review.
Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3).
Dekkers S, Comez D, Karsai N, Arimont-Segura M, Canals M, Caspar B, de Graaf C, Kilpatrick LE, Leurs R, Kellam B, Hill SJ, Briddon SJ, Stocks MJ. Dekkers S, et al. Among authors: caspar b. ACS Med Chem Lett. 2023 Dec 8;15(1):143-148. doi: 10.1021/acsmedchemlett.3c00469. eCollection 2024 Jan 11. ACS Med Chem Lett. 2023. PMID: 38229752 Free PMC article.
Spermine and spermidine bind CXCR4 and inhibit CXCR4- but not CCR5-tropic HIV-1 infection.
Harms M, Smith N, Han M, Groß R, von Maltitz P, Stürzel C, Ruiz-Blanco YB, Almeida-Hernández Y, Rodriguez-Alfonso A, Cathelin D, Caspar B, Tahar B, Sayettat S, Bekaddour N, Vanshylla K, Kleipass F, Wiese S, Ständker L, Klein F, Lagane B, Boonen A, Schols D, Benichou S, Sanchez-Garcia E, Herbeuval JP, Münch J. Harms M, et al. Among authors: caspar b. Sci Adv. 2023 Jul 7;9(27):eadf8251. doi: 10.1126/sciadv.adf8251. Epub 2023 Jul 5. Sci Adv. 2023. PMID: 37406129 Free PMC article.
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