Castaigne JP - Search Results

1

Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties.

Demeule M, Beaudet N, Régina A, Besserer-Offroy É, Murza A, Tétreault P, Belleville K, Ché C, Larocque A, Thiot C, Béliveau R, Longpré JM, Marsault É, Leduc R, Lachowicz JE, Gonias SL, Castaigne JP, Sarret P. Demeule M, et al. Among authors: castaigne jp. J Clin Invest. 2014 Mar;124(3):1199-213. doi: 10.1172/JCI70647. Epub 2014 Feb 17. J Clin Invest. 2014. PMID: 24531547 Free PMC article.

2

ANG4043, a novel brain-penetrant peptide-mAb conjugate, is efficacious against HER2-positive intracranial tumors in mice.

Regina A, Demeule M, Tripathy S, Lord-Dufour S, Currie JC, Iddir M, Annabi B, Castaigne JP, Lachowicz JE. Regina A, et al. Among authors: castaigne jp. Mol Cancer Ther. 2015 Jan;14(1):129-40. doi: 10.1158/1535-7163.MCT-14-0399. Epub 2014 Dec 9. Mol Cancer Ther. 2015. PMID: 25492620

3

New Angiopep-modified doxorubicin (ANG1007) and etoposide (ANG1009) chemotherapeutics with increased brain penetration.

Ché C, Yang G, Thiot C, Lacoste MC, Currie JC, Demeule M, Régina A, Béliveau R, Castaigne JP. Ché C, et al. Among authors: castaigne jp. J Med Chem. 2010 Apr 8;53(7):2814-24. doi: 10.1021/jm9016637. J Med Chem. 2010. PMID: 20210346

4

Identification and design of peptides as a new drug delivery system for the brain.

Demeule M, Régina A, Ché C, Poirier J, Nguyen T, Gabathuler R, Castaigne JP, Béliveau R. Demeule M, et al. Among authors: castaigne jp. J Pharmacol Exp Ther. 2008 Mar;324(3):1064-72. doi: 10.1124/jpet.107.131318. Epub 2007 Dec 21. J Pharmacol Exp Ther. 2008. PMID: 18156463

5

Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector angiopep-2.

Demeule M, Currie JC, Bertrand Y, Ché C, Nguyen T, Régina A, Gabathuler R, Castaigne JP, Béliveau R. Demeule M, et al. Among authors: castaigne jp. J Neurochem. 2008 Aug;106(4):1534-44. doi: 10.1111/j.1471-4159.2008.05492.x. Epub 2008 May 19. J Neurochem. 2008. PMID: 18489712 Free article.

6

Transport characteristics of a novel peptide platform for CNS therapeutics.

Bertrand Y, Currie JC, Demeule M, Régina A, Ché C, Abulrob A, Fatehi D, Sartelet H, Gabathuler R, Castaigne JP, Stanimirovic D, Béliveau R. Bertrand Y, et al. Among authors: castaigne jp. J Cell Mol Med. 2010 Dec;14(12):2827-39. doi: 10.1111/j.1582-4934.2009.00930.x. J Cell Mol Med. 2010. PMID: 19818094 Free PMC article.

7

Synthesis and in vitro analysis of atrial natriuretic peptide-albumin conjugates.

Léger R, Robitaille M, Quraishi O, Denholm E, Benquet C, Carette J, van Wyk P, Pellerin I, Bousquet-Gagnon N, Castaigne JP, Bridon D. Léger R, et al. Among authors: castaigne jp. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3571-5. doi: 10.1016/s0960-894x(03)00790-x. Bioorg Med Chem Lett. 2003. PMID: 14505673

8

Identification of CJC-1131-albumin bioconjugate as a stable and bioactive GLP-1(7-36) analog.

Léger R, Thibaudeau K, Robitaille M, Quraishi O, van Wyk P, Bousquet-Gagnon N, Carette J, Castaigne JP, Bridon DP. Léger R, et al. Among authors: castaigne jp. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4395-8. doi: 10.1016/j.bmcl.2004.06.066. Bioorg Med Chem Lett. 2004. PMID: 15357960

9

Synthesis and evaluation of insulin-human serum albumin conjugates.

Thibaudeau K, Léger R, Huang X, Robitaille M, Quraishi O, Soucy C, Bousquet-Gagnon N, van Wyk P, Paradis V, Castaigne JP, Bridon D. Thibaudeau K, et al. Among authors: castaigne jp. Bioconjug Chem. 2005 Jul-Aug;16(4):1000-8. doi: 10.1021/bc050102k. Bioconjug Chem. 2005. PMID: 16029043

10

Pharmacokinetics and tolerability of a novel long-acting glucagon-like peptide-1 analog, CJC-1131, in healthy and diabetic subjects.

Tiessen RG, Castaigne JP, Dreyfus JF, Nemansky M, Kruizinga HH, van Vliet AA. Tiessen RG, et al. Among authors: castaigne jp. Int J Clin Pharmacol Ther. 2008 Sep;46(9):443-52. doi: 10.5414/cpp46443. Int J Clin Pharmacol Ther. 2008. PMID: 18793574 Clinical Trial.

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