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Page 1
MYC multimers shield stalled replication forks from RNA polymerase.
Nature. 2022 Dec;612(7938):148-155. doi: 10.1038/s41586-022-05469-4. Epub 2022 Nov 23.
Nature. 2022.
PMID: 36424410
MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression.
Giansanti C, Manzini V, Dickmanns A, Dickmanns A, Palumbieri MD, Sanchi A, Kienle SM, Rieth S, Scheffner M, Lopes M, Dobbelstein M.
Giansanti C, et al.
Cell Rep. 2022 May 31;39(9):110879. doi: 10.1016/j.celrep.2022.110879.
Cell Rep. 2022.
PMID: 35649362
Free article.
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The interplay of TARG1 and PARG protects against genomic instability.
Groslambert J, Prokhorova E, Wondisford AR, Tromans-Coia C, Giansanti C, Jansen J, Timinszky G, Dobbelstein M, Ahel D, O'Sullivan RJ, Ahel I.
Groslambert J, et al. Among authors: giansanti c.
Cell Rep. 2023 Sep 26;42(9):113113. doi: 10.1016/j.celrep.2023.113113. Epub 2023 Sep 6.
Cell Rep. 2023.
PMID: 37676774
Free PMC article.
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Self-reversal facilitates the resolution of HMCES DNA-protein crosslinks in cells.
Rua-Fernandez J, Lovejoy CA, Mehta KPM, Paulin KA, Toudji YT, Giansanti C, Eichman BF, Cortez D.
Rua-Fernandez J, et al. Among authors: giansanti c.
Cell Rep. 2023 Nov 28;42(11):113427. doi: 10.1016/j.celrep.2023.113427. Epub 2023 Nov 11.
Cell Rep. 2023.
PMID: 37950866
Free PMC article.
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Mdm4 supports DNA replication in a p53-independent fashion.
Wohlberedt K, Klusmann I, Derevyanko PK, Henningsen K, Choo JAMY, Manzini V, Magerhans A, Giansanti C, Eischen CM, Jochemsen AG, Dobbelstein M.
Wohlberedt K, et al. Among authors: giansanti c.
Oncogene. 2020 Jun;39(25):4828-4843. doi: 10.1038/s41388-020-1325-1. Epub 2020 May 19.
Oncogene. 2020.
PMID: 32427989
Free PMC article.
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MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts.
Papadopoulos D, Solvie D, Baluapuri A, Endres T, Ha SA, Herold S, Kalb J, Giansanti C, Schülein-Völk C, Ade CP, Schneider C, Gaballa A, Vos S, Fischer U, Dobbelstein M, Wolf E, Eilers M.
Papadopoulos D, et al. Among authors: giansanti c.
Mol Cell. 2022 Jan 6;82(1):159-176.e12. doi: 10.1016/j.molcel.2021.11.002. Epub 2021 Nov 29.
Mol Cell. 2022.
PMID: 34847357
Free article.
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Combined inhibition of Aurora-A and ATR kinase results in regression of MYCN-amplified neuroblastoma.
Roeschert I, Poon E, Henssen AG, Garcia HD, Gatti M, Giansanti C, Jamin Y, Ade CP, Gallant P, Schülein-Völk C, Beli P, Richards M, Rosenfeldt M, Altmeyer M, Anderson J, Eggert A, Dobbelstein M, Bayliss R, Chesler L, Büchel G, Eilers M.
Roeschert I, et al. Among authors: giansanti c.
Nat Cancer. 2021 Mar;2(3):312-326. doi: 10.1038/s43018-020-00171-8. Epub 2021 Feb 11.
Nat Cancer. 2021.
PMID: 33768209
Free PMC article.
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