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(18 results)?
Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML.
Mol Cancer Ther. 2022 May 4;21(5):703-714. doi: 10.1158/1535-7163.MCT-21-0185.
Mol Cancer Ther. 2022.
PMID: 35247918
MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia.
Sanjiv K, Calderón-Montaño JM, Pham TM, Erkers T, Tsuber V, Almlöf I, Höglund A, Heshmati Y, Seashore-Ludlow B, Nagesh Danda A, Gad H, Wiita E, Göktürk C, Rasti A, Friedrich S, Centio A, Estruch M, Våtsveen TK, Struyf N, Visnes T, Scobie M, Koolmeister T, Henriksson M, Wallner O, Sandvall T, Lehmann S, Theilgaard-Mönch K, Garnett MJ, Östling P, Walfridsson J, Helleday T, Warpman Berglund U.
Sanjiv K, et al. Among authors: centio a.
Cancer Res. 2021 Nov 15;81(22):5733-5744. doi: 10.1158/0008-5472.CAN-21-0061. Epub 2021 Sep 30.
Cancer Res. 2021.
PMID: 34593524
Free PMC article.
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Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy.
Estruch M, Reckzeh K, Vittori C, Centio A, Ali M, Engelhard S, Zhao L, Won KJ, Liu P, Porse BT, Theilgaard-Mönch K.
Estruch M, et al. Among authors: centio a.
Leukemia. 2021 Jul;35(7):2030-2042. doi: 10.1038/s41375-020-01094-0. Epub 2020 Dec 9.
Leukemia. 2021.
PMID: 33299144
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