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A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia-reperfusion injury.
Fiordaliso F, Chimenti S, Staszewsky L, Bai A, Carlo E, Cuccovillo I, Doni M, Mengozzi M, Tonelli R, Ghezzi P, Coleman T, Brines M, Cerami A, Latini R. Fiordaliso F, et al. Among authors: cerami a. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2046-51. doi: 10.1073/pnas.0409329102. Epub 2005 Jan 25. Proc Natl Acad Sci U S A. 2005. PMID: 15671158 Free PMC article.
Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo.
Erbayraktar S, Grasso G, Sfacteria A, Xie QW, Coleman T, Kreilgaard M, Torup L, Sager T, Erbayraktar Z, Gokmen N, Yilmaz O, Ghezzi P, Villa P, Fratelli M, Casagrande S, Leist M, Helboe L, Gerwein J, Christensen S, Geist MA, Pedersen LØ, Cerami-Hand C, Wuerth JP, Cerami A, Brines M. Erbayraktar S, et al. Among authors: cerami hand c, cerami a. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6741-6. doi: 10.1073/pnas.1031753100. Epub 2003 May 13. Proc Natl Acad Sci U S A. 2003. PMID: 12746497 Free PMC article.
Erythropoietin both protects from and reverses experimental diabetic neuropathy.
Bianchi R, Buyukakilli B, Brines M, Savino C, Cavaletti G, Oggioni N, Lauria G, Borgna M, Lombardi R, Cimen B, Comelekoglu U, Kanik A, Tataroglu C, Cerami A, Ghezzi P. Bianchi R, et al. Among authors: cerami a. Proc Natl Acad Sci U S A. 2004 Jan 20;101(3):823-8. doi: 10.1073/pnas.0307823100. Epub 2004 Jan 12. Proc Natl Acad Sci U S A. 2004. PMID: 14718663 Free PMC article.
Derivatives of erythropoietin that are tissue protective but not erythropoietic.
Leist M, Ghezzi P, Grasso G, Bianchi R, Villa P, Fratelli M, Savino C, Bianchi M, Nielsen J, Gerwien J, Kallunki P, Larsen AK, Helboe L, Christensen S, Pedersen LO, Nielsen M, Torup L, Sager T, Sfacteria A, Erbayraktar S, Erbayraktar Z, Gokmen N, Yilmaz O, Cerami-Hand C, Xie QW, Coleman T, Cerami A, Brines M. Leist M, et al. Among authors: cerami hand c, cerami a. Science. 2004 Jul 9;305(5681):239-42. doi: 10.1126/science.1098313. Science. 2004. PMID: 15247477
453 results