Chahwan R - Search Results

1

Crosstalk between genetic and epigenetic information through cytosine deamination.

Chahwan R, Wontakal SN, Roa S. Chahwan R, et al. Trends Genet. 2010 Oct;26(10):443-8. doi: 10.1016/j.tig.2010.07.005. Epub 2010 Aug 26. Trends Genet. 2010. PMID: 20800313

2

The multidimensional nature of epigenetic information and its role in disease.

Chahwan R, Wontakal SN, Roa S. Chahwan R, et al. Discov Med. 2011 Mar;11(58):233-43. Discov Med. 2011. PMID: 21447282 Free article. Review.

3

Mismatch-mediated error prone repair at the immunoglobulin genes.

Chahwan R, Edelmann W, Scharff MD, Roa S. Chahwan R, et al. Biomed Pharmacother. 2011 Dec;65(8):529-36. doi: 10.1016/j.biopha.2011.09.001. Epub 2011 Oct 24. Biomed Pharmacother. 2011. PMID: 22100214 Free PMC article. Review.

4

The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination.

Chahwan R, van Oers JM, Avdievich E, Zhao C, Edelmann W, Scharff MD, Roa S. Chahwan R, et al. J Exp Med. 2012 Apr 9;209(4):671-8. doi: 10.1084/jem.20111531. Epub 2012 Mar 26. J Exp Med. 2012. PMID: 22451719 Free PMC article.

5

AIDing antibody diversity by error-prone mismatch repair.

Chahwan R, Edelmann W, Scharff MD, Roa S. Chahwan R, et al. Semin Immunol. 2012 Aug;24(4):293-300. doi: 10.1016/j.smim.2012.05.005. Epub 2012 Jun 14. Semin Immunol. 2012. PMID: 22703640 Free PMC article. Review.

6

Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes.

Schaetzlein S, Chahwan R, Avdievich E, Roa S, Wei K, Eoff RL, Sellers RS, Clark AB, Kunkel TA, Scharff MD, Edelmann W. Schaetzlein S, et al. Among authors: chahwan r. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2470-9. doi: 10.1073/pnas.1308512110. Epub 2013 Jun 10. Proc Natl Acad Sci U S A. 2013. PMID: 23754438 Free PMC article.

7

Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1D173A mice.

Wang S, Lee K, Gray S, Zhang Y, Tang C, Morrish RB, Tosti E, van Oers J, Amin MR, Cohen PE, MacCarthy T, Roa S, Scharff MD, Edelmann W, Chahwan R. Wang S, et al. Among authors: chahwan r. Nucleic Acids Res. 2022 Aug 12;50(14):8093-8106. doi: 10.1093/nar/gkac616. Nucleic Acids Res. 2022. PMID: 35849338 Free PMC article.

8

The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination.

Ramachandran S, Chahwan R, Nepal RM, Frieder D, Panier S, Roa S, Zaheen A, Durocher D, Scharff MD, Martin A. Ramachandran S, et al. Among authors: chahwan r. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):809-14. doi: 10.1073/pnas.0913790107. Epub 2009 Dec 22. Proc Natl Acad Sci U S A. 2010. PMID: 20080757 Free PMC article.

9

APOBECs orchestrate genomic and epigenomic editing across health and disease.

Cervantes-Gracia K, Gramalla-Schmitz A, Weischedel J, Chahwan R. Cervantes-Gracia K, et al. Among authors: chahwan r. Trends Genet. 2021 Nov;37(11):1028-1043. doi: 10.1016/j.tig.2021.07.003. Epub 2021 Aug 2. Trends Genet. 2021. PMID: 34353635 Free article. Review.

10

Overlapping hotspots in CDRs are critical sites for V region diversification.

Wei L, Chahwan R, Wang S, Wang X, Pham PT, Goodman MF, Bergman A, Scharff MD, MacCarthy T. Wei L, et al. Among authors: chahwan r. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E728-37. doi: 10.1073/pnas.1500788112. Epub 2015 Feb 2. Proc Natl Acad Sci U S A. 2015. PMID: 25646473 Free PMC article.

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