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Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice.
Krishnan SM, Dowling JK, Ling YH, Diep H, Chan CT, Ferens D, Kett MM, Pinar A, Samuel CS, Vinh A, Arumugam TV, Hewitson TD, Kemp-Harper BK, Robertson AA, Cooper MA, Latz E, Mansell A, Sobey CG, Drummond GR. Krishnan SM, et al. Among authors: chan ct. Br J Pharmacol. 2016 Feb;173(4):752-65. doi: 10.1111/bph.13230. Epub 2015 Jul 31. Br J Pharmacol. 2016. PMID: 26103560 Free PMC article.
Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension.
Krishnan SM, Ling YH, Huuskes BM, Ferens DM, Saini N, Chan CT, Diep H, Kett MM, Samuel CS, Kemp-Harper BK, Robertson AAB, Cooper MA, Peter K, Latz E, Mansell AS, Sobey CG, Drummond GR, Vinh A. Krishnan SM, et al. Among authors: chan ct. Cardiovasc Res. 2019 Mar 15;115(4):776-787. doi: 10.1093/cvr/cvy252. Cardiovasc Res. 2019. PMID: 30357309 Free PMC article.
M2 macrophage accumulation in the aortic wall during angiotensin II infusion in mice is associated with fibrosis, elastin loss, and elevated blood pressure.
Moore JP, Vinh A, Tuck KL, Sakkal S, Krishnan SM, Chan CT, Lieu M, Samuel CS, Diep H, Kemp-Harper BK, Tare M, Ricardo SD, Guzik TJ, Sobey CG, Drummond GR. Moore JP, et al. Among authors: chan ct. Am J Physiol Heart Circ Physiol. 2015 Sep;309(5):H906-17. doi: 10.1152/ajpheart.00821.2014. Epub 2015 Jun 12. Am J Physiol Heart Circ Physiol. 2015. PMID: 26071547 Free article.
Obligatory Role for B Cells in the Development of Angiotensin II-Dependent Hypertension.
Chan CT, Sobey CG, Lieu M, Ferens D, Kett MM, Diep H, Kim HA, Krishnan SM, Lewis CV, Salimova E, Tipping P, Vinh A, Samuel CS, Peter K, Guzik TJ, Kyaw TS, Toh BH, Bobik A, Drummond GR. Chan CT, et al. Hypertension. 2015 Nov;66(5):1023-33. doi: 10.1161/HYPERTENSIONAHA.115.05779. Epub 2015 Sep 8. Hypertension. 2015. PMID: 26351030
Antibodies in the pathogenesis of hypertension.
Chan CT, Lieu M, Toh BH, Kyaw TS, Bobik A, Sobey CG, Drummond GR. Chan CT, et al. Biomed Res Int. 2014;2014:504045. doi: 10.1155/2014/504045. Epub 2014 Jun 23. Biomed Res Int. 2014. PMID: 25050352 Free PMC article. Review.
715 results