Chan HYE - Search Results

1

A peptidylic inhibitor for neutralizing expanded CAG RNA-induced nucleolar stress in polyglutamine diseases.

Zhang Q, Chen ZS, An Y, Liu H, Hou Y, Li W, Lau KF, Koon AC, Ngo JCK, Chan HYE. Zhang Q, et al. Among authors: chan hye. RNA. 2018 Apr;24(4):486-498. doi: 10.1261/rna.062703.117. Epub 2018 Jan 2. RNA. 2018. PMID: 29295891 Free PMC article.

2

Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.

Chan WM, Tsoi H, Wu CC, Wong CH, Cheng TC, Li HY, Lau KF, Shaw PC, Perrimon N, Chan HY. Chan WM, et al. Hum Mol Genet. 2011 May 1;20(9):1738-50. doi: 10.1093/hmg/ddr049. Epub 2011 Feb 7. Hum Mol Genet. 2011. PMID: 21300695

3

GULP1 is a novel APP-interacting protein that alters APP processing.

Hao Y, Perkinton MS, Chan WW, Chan HY, Miller CC, Lau KF. Hao Y, et al. Biochem J. 2011 Jun 15;436(3):631-9. doi: 10.1042/BJ20110145. Biochem J. 2011. PMID: 21486224

4

Genomic organization and promoter cloning of the human X11α gene APBA1.

Chai KH, McLoughlin DM, Chan TF, Chan HY, Lau KF. Chai KH, et al. DNA Cell Biol. 2012 May;31(5):651-9. doi: 10.1089/dna.2011.1447. Epub 2011 Dec 2. DNA Cell Biol. 2012. PMID: 22136355

5

Promoter characterization and genomic organization of the human X11β gene APBA2.

Hao Y, Chai KH, McLoughlin DM, Chan HY, Lau KF. Hao Y, et al. Neuroreport. 2012 Feb 15;23(3):146-51. doi: 10.1097/WNR.0b013e32834f1934. Neuroreport. 2012. PMID: 22222501

6

Degradation of mutant huntingtin via the ubiquitin/proteasome system is modulated by FE65.

Chow WN, Luk HW, Chan HY, Lau KF. Chow WN, et al. Biochem J. 2012 May 1;443(3):681-9. doi: 10.1042/BJ20112175. Biochem J. 2012. PMID: 22352297

7

CAG expansion induces nucleolar stress in polyglutamine diseases.

Tsoi H, Lau TC, Tsang SY, Lau KF, Chan HY. Tsoi H, et al. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13428-33. doi: 10.1073/pnas.1204089109. Epub 2012 Jul 30. Proc Natl Acad Sci U S A. 2012. PMID: 22847428 Free PMC article.

8

Expression of expanded CAG transcripts triggers nucleolar stress in Huntington's disease.

Tsoi H, Chan HY. Tsoi H, et al. Cerebellum. 2013 Jun;12(3):310-2. doi: 10.1007/s12311-012-0447-6. Cerebellum. 2013. PMID: 23315009

9

FE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowth.

Cheung HN, Dunbar C, Mórotz GM, Cheng WH, Chan HY, Miller CC, Lau KF. Cheung HN, et al. FASEB J. 2014 Jan;28(1):337-49. doi: 10.1096/fj.13-232694. Epub 2013 Sep 20. FASEB J. 2014. PMID: 24056087 Free PMC article.

10

Roles of the nucleolus in the CAG RNA-mediated toxicity.

Tsoi H, Chan HY. Tsoi H, et al. Biochim Biophys Acta. 2014 Jun;1842(6):779-84. doi: 10.1016/j.bbadis.2013.11.015. Epub 2013 Nov 20. Biochim Biophys Acta. 2014. PMID: 24269666 Free article. Review.

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