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Targeted manipulation of mammalian genomes using designed zinc finger nucleases.
Kandavelou K, Ramalingam S, London V, Mani M, Wu J, Alexeev V, Civin CI, Chandrasegaran S. Kandavelou K, et al. Among authors: chandrasegaran s. Biochem Biophys Res Commun. 2009 Oct 9;388(1):56-61. doi: 10.1016/j.bbrc.2009.07.112. Epub 2009 Jul 25. Biochem Biophys Res Commun. 2009. PMID: 19635463 Free PMC article.
Creating designed zinc-finger nucleases with minimal cytotoxicity.
Ramalingam S, Kandavelou K, Rajenderan R, Chandrasegaran S. Ramalingam S, et al. Among authors: chandrasegaran s. J Mol Biol. 2011 Jan 21;405(3):630-41. doi: 10.1016/j.jmb.2010.10.043. Epub 2010 Nov 19. J Mol Biol. 2011. PMID: 21094162 Free PMC article.
Synthetic chromosome arms function in yeast and generate phenotypic diversity by design.
Dymond JS, Richardson SM, Coombes CE, Babatz T, Muller H, Annaluru N, Blake WJ, Schwerzmann JW, Dai J, Lindstrom DL, Boeke AC, Gottschling DE, Chandrasegaran S, Bader JS, Boeke JD. Dymond JS, et al. Among authors: chandrasegaran s. Nature. 2011 Sep 14;477(7365):471-6. doi: 10.1038/nature10403. Nature. 2011. PMID: 21918511 Free PMC article.
Assembling DNA fragments by USER fusion.
Annaluru N, Muller H, Ramalingam S, Kandavelou K, London V, Richardson SM, Dymond JS, Cooper EM, Bader JS, Boeke JD, Chandrasegaran S. Annaluru N, et al. Among authors: chandrasegaran s. Methods Mol Biol. 2012;852:77-95. doi: 10.1007/978-1-61779-564-0_7. Methods Mol Biol. 2012. PMID: 22328427
Assembling large DNA segments in yeast.
Muller H, Annaluru N, Schwerzmann JW, Richardson SM, Dymond JS, Cooper EM, Bader JS, Boeke JD, Chandrasegaran S. Muller H, et al. Among authors: chandrasegaran s. Methods Mol Biol. 2012;852:133-50. doi: 10.1007/978-1-61779-564-0_11. Methods Mol Biol. 2012. PMID: 22328431
The Build-a-Genome course.
Cooper EM, Müller H, Chandrasegaran S, Bader JS, Boeke JD. Cooper EM, et al. Among authors: chandrasegaran s. Methods Mol Biol. 2012;852:273-83. doi: 10.1007/978-1-61779-564-0_20. Methods Mol Biol. 2012. PMID: 22328440
65 results