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Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy.
Moens AL, Takimoto E, Tocchetti CG, Chakir K, Bedja D, Cormaci G, Ketner EA, Majmudar M, Gabrielson K, Halushka MK, Mitchell JB, Biswal S, Channon KM, Wolin MS, Alp NJ, Paolocci N, Champion HC, Kass DA. Moens AL, et al. Among authors: channon km. Circulation. 2008 May 20;117(20):2626-36. doi: 10.1161/CIRCULATIONAHA.107.737031. Epub 2008 May 12. Circulation. 2008. PMID: 18474817 Free PMC article.
Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3-adrenoreceptor.
Moens AL, Leyton-Mange JS, Niu X, Yang R, Cingolani O, Arkenbout EK, Champion HC, Bedja D, Gabrielson KL, Chen J, Xia Y, Hale AB, Channon KM, Halushka MK, Barker N, Wuyts FL, Kaminski PM, Wolin MS, Kass DA, Barouch LA. Moens AL, et al. Among authors: channon km. J Mol Cell Cardiol. 2009 Nov;47(5):576-85. doi: 10.1016/j.yjmcc.2009.06.005. Epub 2009 Sep 18. J Mol Cell Cardiol. 2009. PMID: 19766235 Free PMC article.
Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression.
Bendall JK, Alp NJ, Warrick N, Cai S, Adlam D, Rockett K, Yokoyama M, Kawashima S, Channon KM. Bendall JK, et al. Among authors: channon km. Circ Res. 2005 Oct 28;97(9):864-71. doi: 10.1161/01.RES.0000187447.03525.72. Epub 2005 Sep 22. Circ Res. 2005. PMID: 16179591
434 results