Charman SA - Search Results

1

Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice.

Gujjar R, El Mazouni F, White KL, White J, Creason S, Shackleford DM, Deng X, Charman WN, Bathurst I, Burrows J, Floyd DM, Matthews D, Buckner FS, Charman SA, Phillips MA, Rathod PK. Gujjar R, et al. Among authors: charman wn, charman sa. J Med Chem. 2011 Jun 9;54(11):3935-49. doi: 10.1021/jm200265b. Epub 2011 May 12. J Med Chem. 2011. PMID: 21517059 Free PMC article.

2

Presystemic acetylation of platelets by aspirin: reduction in rate of drug delivery to improve biochemical selectivity for thromboxane A2.

FitzGerald GA, Lupinetti M, Charman SA, Charman WN. FitzGerald GA, et al. Among authors: charman wn, charman sa. J Pharmacol Exp Ther. 1991 Dec;259(3):1043-9. J Pharmacol Exp Ther. 1991. PMID: 1762060

3

Techniques for assessing the effects of pharmaceutical excipients on the aggregation of porcine growth hormone.

Charman SA, Mason KL, Charman WN. Charman SA, et al. Among authors: charman wn. Pharm Res. 1993 Jul;10(7):954-62. doi: 10.1023/a:1018994102218. Pharm Res. 1993. PMID: 8378257

4

Lymphatic transport of halofantrine in the triple-cannulated anesthetized rat model: effect of lipid vehicle dispersion.

Porter CJ, Charman SA, Charman WN. Porter CJ, et al. Among authors: charman wn, charman sa. J Pharm Sci. 1996 Apr;85(4):351-6. doi: 10.1021/js950221g. J Pharm Sci. 1996. PMID: 8901067

5

Lymphatic transport of halofantrine in the conscious rat when administered as either the free base or the hydrochloride salt: effect of lipid class and lipid vehicle dispersion.

Porter CJ, Charman SA, Humberstone AJ, Charman WN. Porter CJ, et al. Among authors: charman wn, charman sa. J Pharm Sci. 1996 Apr;85(4):357-61. doi: 10.1021/js9502229. J Pharm Sci. 1996. PMID: 8901068

6

The application of capillary electrophoresis for monitoring effects of excipients on protein conformation.

McIntosh KA, Charman WN, Charman SA. McIntosh KA, et al. Among authors: charman wn, charman sa. J Pharm Biomed Anal. 1998 Feb;16(6):1097-105. doi: 10.1016/s0731-7085(97)00096-4. J Pharm Biomed Anal. 1998. PMID: 9547715

7

Variation in the diffusion and release of ribonuclease through and from esterified hyaluronic acid membranes: effect of changes in matrix characteristics.

Simon LD, Stella VJ, Charman WN, Charman SA. Simon LD, et al. Among authors: charman wn, charman sa. J Control Release. 1999 Aug 27;61(1-2):159-64. doi: 10.1016/s0168-3659(99)00115-7. J Control Release. 1999. PMID: 10469912

8

Mechanisms controlling diffusion and release of model proteins through and from partially esterified hyaluronic acid membranes.

Simon LD, Stella VJ, Charman WN, Charman SA. Simon LD, et al. Among authors: charman wn, charman sa. J Control Release. 1999 Sep 20;61(3):267-79. doi: 10.1016/s0168-3659(99)00123-6. J Control Release. 1999. PMID: 10477800

9

A novel prodrug approach for tertiary amines. 3. In vivo evaluation of two N-phosphonooxymethyl prodrugs in rats and dogs.

Krise JP, Charman WN, Charman SA, Stella VJ. Krise JP, et al. Among authors: charman wn, charman sa. J Pharm Sci. 1999 Sep;88(9):928-32. doi: 10.1021/js980382v. J Pharm Sci. 1999. PMID: 10479356

10

Identification of an antimalarial synthetic trioxolane drug development candidate.

Vennerstrom JL, Arbe-Barnes S, Brun R, Charman SA, Chiu FC, Chollet J, Dong Y, Dorn A, Hunziker D, Matile H, McIntosh K, Padmanilayam M, Santo Tomas J, Scheurer C, Scorneaux B, Tang Y, Urwyler H, Wittlin S, Charman WN. Vennerstrom JL, et al. Among authors: charman wn, charman sa. Nature. 2004 Aug 19;430(7002):900-4. doi: 10.1038/nature02779. Nature. 2004. PMID: 15318224 Free article.

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